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Synthesis and antitumor evaluation of the presumed cytotoxic metabolites of spermine and N,N'-bis(3-aminopropyl)nonane-1,9-diamine Mervyn Israel, Estelle C. Zoll, Naseem Muhammad, and Edward J. Modest pp 1 - 5; DOI: 10.1021/jm00259a001 |
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New specific angiotensin antagonists. [8-Valine]-, [8-isoleucine]-, and chlorambucil-des-1-aspartic, 8-valine-angiotensins I A. C. M. Paiva, V. L. A. Nouailhetas, M. E. Miyamoto, G. B. Mendes, and T. B. Paiva pp 6 - 9; DOI: 10.1021/jm00259a002 |
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Novel analgesics and molecular rearrangements in the morphine-thebaine group. 28. Derivatives of 6,14-endo-etheno-7-Oxo-6,7,8,14-tetrahydrothebaine and 6,14-endo-etheno-6,7,8,14-tetrahydrothebaine John W. Lewis, Michael J. Readhead, and Alan C. B. Smith pp 9 - 12; DOI: 10.1021/jm00259a003 |
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Novel analgetics and molecular rearrangements in the morphine-thebaine group. 30. 16-Alkyl-6,14-endo-ethenotetrahydrothebaines John W. Lewis, Philip A. Mayor, and David I. Haddlesey pp 12 - 14; DOI: 10.1021/jm00259a004 |
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Conformational study of phenethylamine receptor sites. 1. Syntheses of semirigid analogs of .beta.-methylamphetamine Edward E. Smissman and Thomas L. Pazdernik pp 14 - 18; DOI: 10.1021/jm00259a005 |
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Conformational study of phenethylamine receptor sites. 2. Synthesis of dl-2-amino-3-phenyl-trans-decalins and dl-2-isopropylamino-3-phenyl-trans-decalins Edward E. Smissman and Thomas L. Pazdernik pp 18 - 23; DOI: 10.1021/jm00259a006 |
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Conformational aspects of systems related to acetylcholine. 5. Syntheses of the dl-2(e)-methyl-, dl-3(e)-methyl-, and dl-2(e),3(e)-dimethyl-3(a)-trimethylammonium-2(a)-acetoxy-trans-decalin halides Edward E. Smissman and George R. Parker pp 23 - 27; DOI: 10.1021/jm00259a007 |
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Cyclobutane analogs of acetyl-.gamma.-homocholine Joseph G. Cannon, Youlin Lin, and John Paul Long pp 27 - 29; DOI: 10.1021/jm00259a008 |
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Mass spectral analysis of glucuronides Stephen Billets, Paul S. Lietman, and Catherine Fenselau pp 30 - 33; DOI: 10.1021/jm00259a009 |
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Biotransformation of 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-3,5-pyridinedicarboxylic acid diethyl ester Sally E. Parker and Joseph Weinstock pp 34 - 37; DOI: 10.1021/jm00259a010 |
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Acyclic puromycin analog. 6-Dimethylamino-9-[2-hydroxy-3-(p-methoxyphenyl-L-alanylamino)propyl]purine Robert Vince and Raymond G. Isakson pp 37 - 40; DOI: 10.1021/jm00259a011 |
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Acridan-4-carboxylic acids and N-aryl-2-amino-3-toluic acids as planar and antiplanar analogs of antiinflammatory N-arylanthranilic acids Tim R. Westby and Charles F. Barfknecht pp 40 - 43; DOI: 10.1021/jm00259a012 |
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1,2-Benzothiazines. 6. 3-Carbamoyl-4-hydroxy-2H-1,2-benzothiazine 1,1-dioxides as antiinflammatory agents Harold Zinnes, Neil A. Lindo, Jagadish C. Sircar, Martin L. Schwartz, and John Shavel pp 44 - 48; DOI: 10.1021/jm00259a013 |
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Synthetic antidiarrheal agents. 1. Approach to the separation of antidiarrheal activity from narcotic analgesic activity Donald E. Butler, Robert F. Meyer, Susan M. Alexander, Paul Bass, and John A. Kennedy pp 49 - 54; DOI: 10.1021/jm00259a014 |
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Irreversible adrenergic .alpha.-receptor antagonism by (R)-and (S)-N-(2-chloroethyl)-N-methyl-2-phenyl-2-hydroxyethylamine and related agents S. McLean, V. C. Swamy, D. Tomei, and D. J. Triggle pp 54 - 57; DOI: 10.1021/jm00259a015 |
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Axonal cholinergic binding macromolecule. Response to neuroactive drugs Jeffrey L. Denburg and Richard D. O'Brien pp 57 - 60; DOI: 10.1021/jm00259a016 |
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Synthesis of methylene- and carbonyl-bridged analogs of iodothyronines and iodothyroacetic acids Spencer L. Tripp, Fred B. Block, and George Barile pp 60 - 64; DOI: 10.1021/jm00259a017 |
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Preparation of 7-chloro steroids Robert W. Guthrie, Alfred Boris, Francis A. Mennona, John G. Mullin, and Richard W. Kierstead pp 65 - 68; DOI: 10.1021/jm00259a018 |
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Antimalarials. 4. 4-Pyridinemethanols with styryl and benzoyl substituents M. P. LaMontagne pp 68 - 72; DOI: 10.1021/jm00259a019 |
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Structure and antischistosomal activity in the nitrofuran series. Requirement for a 5-nitro-2-furyl-vinyl moiety based on comparison of 3-(5-nitro-2-furyl)-substituted propionic, acrylic, and propiolic acid derivatives P. B. Hulbert, E. Bueding, and C. H. Robinson pp 72 - 78; DOI: 10.1021/jm00259a020 |
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Structure and antischistosomal activity in the nitrofuran series. Requirement for a 5-nitro group in 3-(5-nitro-2-furyl)acrylic acid derivatives C. H. Robinson, S. Spengel, and E. Bueding pp 79 - 80; DOI: 10.1021/jm00259a021 |
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Nucleoside peptides. 5. Synthesis of certain N-(5-uridineacetyl)amino acids from 5-uridineacetic acid George A. Ivanovics, H. Robert Wilson, Robert J. Rousseau, and Roland K. Robins pp 80 - 83; DOI: 10.1021/jm00259a022 |
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Luteinizing hormone releasing hormone. Solid-phase synthesis of a 5-phenylalanine analog possessing high biological activity David H. Coy, Esther J. Coy, and Andrew V. Schally pp 83 - 84; DOI: 10.1021/jm00259a023 |
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Novel analgetics and molecular rearrangements in the morphine-thebaine group. 29. Aryl and arylalkyl tertiary alcohols in the 6,14-endo-ethenotetrahydrothebaine series John W. Lewis and Michael J. Readhead pp 84 - 85; DOI: 10.1021/jm00259a024 |
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Penicillinase inhibition Ted A. Baer and Mathias P. Mertes pp 85 - 87; DOI: 10.1021/jm00259a025 |
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Benzopyrones. 9. Synthesis and pharmacology of some novel bischromones G. Barker, G. P. Ellis, and D. Shaw pp 87 - 89; DOI: 10.1021/jm00259a026 |
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Antimalarials. Some 9-substituted amino-6-chloro-2-methoxyacridines Tara Singh, Robert G. Stein, and John H. Biel pp 89 - 90; DOI: 10.1021/jm00259a027 |
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Synthesis of an androgenic-anabolic nonsteroid Galal Zanati and Manfred E. Wolff pp 90 - 91; DOI: 10.1021/jm00259a028 |
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Book Reviews Alfred Burger pp 92 - 92; DOI: 10.1021/jm00259a600 |
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Circular dichroism studies of aryl diastereoisomers. 2. Dependence of 1Lb transition sign upon the nature of the p-substituent in various chloramphenicol derivatives Lester A. Mitscher, Peter W. Howison, Jules B. LaPidus, and Theodore D. Sokoloski pp 93 - 97; DOI: 10.1021/jm00260a001 |
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Circular dichroism studies of aryl diastereoisomers. 3. Cupra A spectra of chloramphenicol derivatives Lester A. Mitscher, Peter W. Howison, and Theodore D. Sokoloski pp 98 - 101; DOI: 10.1021/jm00260a002 |
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Inhibition of phenylethanolamine N-methyl transferase by benzylamines. 1. Structure-activity relations Ray W. Fuller, Bryan B. Molloy, William A. Day, Betty Warren Roush, and Max M. Marsh pp 101 - 106; DOI: 10.1021/jm00260a003 |
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Inhibition of phenylethanolamine N-methyltransferase by benzylamines. 2. In vitro and in vivo studies with 2,3-dichloro-.alpha.-methylbenzylamine Ray W. Fuller, Betty Warren Roush, Harold D. Snoddy, and Bryan B. Molloy pp 106 - 109; DOI: 10.1021/jm00260a004 |
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Syntheses of cisoid and transoid analogs of phenethylamine Edward E. Smissman, Samir El-Antably, Loren W. Hedrich, Edward J. Walaszek, and L. F. Tseng pp 109 - 113; DOI: 10.1021/jm00260a005 |
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Synthesis and antifertility activity of some oximinoandrostenes Arvin P. Shroff, C. H. Harper, G. O. Allen, and R. P. Blye pp 113 - 115; DOI: 10.1021/jm00260a006 |
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Coenzyme Q. 153. Antimetabolites of coenzyme Q 16. New alkylmercaptoquinones having antimalarial curative activity Thomas H. Porter, Christine M. Bowman, and Karl Folkers pp 115 - 118; DOI: 10.1021/jm00260a007 |
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3-Phenyl-5-quinolinemethanol antimalarials Alexandros Makriyannis, James W. Wilson, and James S. Frazee pp 118 - 122; DOI: 10.1021/jm00260a008 |
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1,3,5(10)-Estratrien-17.beta.-yl enol ethers and acetals. New classes of orally and parenterally active estrogenic derivatives Rinaldo Gardi, Romano Vitali, Giovanni Falconi, and Alberto Ercoli pp 123 - 127; DOI: 10.1021/jm00260a009 |
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Aminobenzoic acid diuretics. 4. 4-Benzyl-5-sulfamylanthranilic acid derivatives and related 1,2-benzisothiazole 1,1-dioxides Peter W. Feit, Ole B. Tvaermose Nielsen, and Niels Rastrup-Andersen pp 127 - 130; DOI: 10.1021/jm00260a010 |
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Antiinflammatory oxindolecarboxanilides Edward H. Wiseman, J. Chiaini, and J. M. McManus pp 131 - 134; DOI: 10.1021/jm00260a011 |
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Antimalarials. 1. Heterocyclic analogs of N-substituted naphthalenebisoxazines Gurdip S. Bajwa, Kenneth E. Hartman, and Madeleine M. Joullie pp 134 - 138; DOI: 10.1021/jm00260a012 |
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Synthesis and biological activity of analogs of naturally occurring 6-ureidopurines and their nucleosides Chung Il Hong, Girish B. Chheda, Shib P. Dutta, Anne O'Grady-Curtis, and George L. Tritsch pp 139 - 147; DOI: 10.1021/jm00260a013 |
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Potential anti-Parkinson drugs designed by receptor mapping Yvonne C. Martin, Charles H. Jarboe, Ruth A. Krause, Kathleen R. Lynn, Daniel Dunnigan, and James B. Holland pp 147 - 150; DOI: 10.1021/jm00260a014 |
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Hydroxyguanidines. New class of antihypertensive agents Denis M. Bailey, C. George DeGrazia, Harlan E. Lape, Richard Frering, Dorothy Fort, and Thomas Skulan pp 151 - 156; DOI: 10.1021/jm00260a015 |
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Diacetoxypiperidinium analogs of acetylcholine Neil J. Lewis, Karen K. Barker, Richard M. Fox, and Mathias P. Mertes pp 156 - 159; DOI: 10.1021/jm00260a016 |
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Solid-phase synthesis and pressor potency of [1-deamino-9-ethylenediamine]-lysine-vasopressin John D. Glass and Vincent Du Vigneaud pp 160 - 161; DOI: 10.1021/jm00260a017 |
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Bis-N,O-diacetylhydroxylamine analog of diaminodiphenyl sulfone possessing antimalarial activity Bernard Loev, Frederick Dowalo, Vassilios J. Theodorides, and Betty P. Vogh pp 161 - 163; DOI: 10.1021/jm00260a018 |
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L-4'-Cyano-3-(2,2,2-trifluoroacetamido)succinanilic acid and related synthetic sweetening agents Milton Lapidus and Marion Sweeney pp 163 - 166; DOI: 10.1021/jm00260a019 |
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Absolute configuration by asymmetric synthesis of (+)-1-(4-acetamidophenoxy)-3-(isopropylamino)propan-2-ol) (practolol) J. C. Danilewicz and J. E. G. Kemp pp 168 - 169; DOI: 10.1021/jm00260a020 |
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Structure of chlorguanide hydrochloride Herman L. Ammon and Linda A. Plastas pp 169 - 171; DOI: 10.1021/jm00260a021 |
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Synthesis and biological activity of (6aS)-10,11-dihydroxyaporphine, the optical antipode of apomorphine Walfred S. Saari, Stella W. King, and Victor J. Lotti pp 171 - 172; DOI: 10.1021/jm00260a022 |
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5-Benzoyl-1-methylpyrrole-2-acetic acids as antiinflammatory agents. 2. 4-Methyl compounds John R. Carson and Stewart Wong pp 172 - 174; DOI: 10.1021/jm00260a023 |
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Hypocholesterolemic 5-methyltetrazole derivatives Ronald L. Buchanan and Vilmars Sprancmanis pp 174 - 175; DOI: 10.1021/jm00260a024 |
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Aldehyde analog of indomethacin Edward J. Glamkowski, George Gal, and Meyer Sletzinger pp 176 - 177; DOI: 10.1021/jm00260a025 |
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Inhibition of catechol amine uptake by conformationally restricted phenethylamine derivatives Duane D. Miller, John Fowble, and Popat N. Patil pp 177 - 178; DOI: 10.1021/jm00260a026 |
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Anticonvulsant and cardiovascular effects of substituted thiazolidones S. Nagar, H. H. Singh, J. N. Sinha, and Surendra S. Parmar pp 178 - 180; DOI: 10.1021/jm00260a027 |
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Synthesis and analgetic activity of the diastereomeric 8-hydroxy-6,7-benzomorphans Jon J. Fauley and Jules B. LaPidus pp 181 - 182; DOI: 10.1021/jm00260a028 |
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Synthesis of 1,2-dihydro-1-(2-deoxy-.beta.-D-erythropentofuranosyl)-2-oxopyrazine 4-oxide, a potent analog of deoxyuridine Phillip T. Berkowitz, Thomas J. Bardos, and Alexander Bloch pp 183 - 184; DOI: 10.1021/jm00260a029 |
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Isolation and Renin-Inhibitory Activity of Phosphoglyceride from Shark Kidney Joseph G. Turcotte, and Robert E. Boyd pp 166 - 168; DOI: 10.1021/jm00260a600 |
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Book Reviews pp 184 - 184; DOI: 10.1021/jm00260a601 |
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2,4-Diaminothieno[2,3-d]pyrimidines as antifolates and antimalarials. 1. Synthesis of 2,4-diamino-5,6,4,8-tetrahydrothianaphtheno[2,3-d]pyrimidines and related compounds A. Rosowsky, M. Chaykovsky, K. K. N. Chen, M. Lin, and E. J. Modest pp 185 - 188; DOI: 10.1021/jm00261a002 |
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2,4-Diaminothieno[2,3-d]pyrimidines as antifolates and antimalarials. 2. Synthesis of 2,4-diaminopyrido[4',3':4,5]thieno[2,3-d]pyrimidines and 2,4-diamino-8H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidines M. Chaykovsky, M. Lin, A. Rosowsky, and E. J. Modest pp 188 - 191; DOI: 10.1021/jm00261a003 |
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2,4-Diaminothieno[2,3-d]pyrimidines as antifolates and antimalarials. 3. Synthesis of 5,6-disubstituted derivatives and related tetracyclic analogs A. Rosowsky, K. K. N. Chen, and M. Lin pp 191 - 194; DOI: 10.1021/jm00261a004 |
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Stereochemical studies on medicinal agents. 12. Distinction of enantiotopic groups in the interaction of 1-methyl-4-phenyl-4-propionoxypiperidine with analgetic receptors Dennis L. Larson and Philip S. Portoghese pp 195 - 198; DOI: 10.1021/jm00261a005 |
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Stereochemical studies on medicinal agents. 13. Correlation of the solid-state conformations of 1,3,5-trimethyl- and 1,3-dimethyl-4-phenyl-4-propionoxypiperidine enantiomers with their absolute stereoselectivity at analgetic receptors Philip S. Portoghese, Zeinab S. D. Gomaa, Dennis L. Larson, and Eli Shefter pp 199 - 203; DOI: 10.1021/jm00261a006 |
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Stereochemical studies on medicinal agents. 14. Relative stereochemistries and analgetic potencies of diastereomeric 3-allyl and 3-propyl derivatives of 1-methyl-4-phenyl-4-propionoxypiperidine Kevin H. Bell and Philip S. Portoghese pp 203 - 205; DOI: 10.1021/jm00261a007 |
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Coenzyme Q. 151. Antimetabolites of coenzyme Q. 14. Quinolinequinone analogs which inhibit mitochondrial DPNH-oxidase and succinoxidase Christine M. Bowman, Frederick S. Skelton, Thomas H. Porter, and Karl Folkers pp 206 - 209; DOI: 10.1021/jm00261a008 |
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Irreversible enzyme inhibitors. 197. Water-soluble reversible inhibitors of dihydrofolate reductase with potent antitumor activity derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine B. R. Baker and Wallace T. Ashton pp 209 - 214; DOI: 10.1021/jm00261a009 |
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Psychotropic drugs. 18. Synthesis and structure-activity relations of 5-phenyl-1,3-dihydro-2H-thieno[2,3-e][1,4]diazepin-2-ones Michio Nakanishi, Tetsuya Tahara, Kazuhiko Araki, Masami Shiroki, Tatsumi Tsumagari, and Yukio Takigawa pp 214 - 219; DOI: 10.1021/jm00261a010 |
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Centrally acting emetics. 7. Hofmann and Emde degradation products of apomorphine Joseph G. Cannon, Robert J. Borgman, Mohd. A. Aleem, and John Paul Long pp 219 - 224; DOI: 10.1021/jm00261a011 |
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Conformational effects on the activity of drugs. 4. Cyclic analogs of 1-(p-nitrophenyl)-2-isopropylaminoethanol. Synthesis and evaluation of the adrenergic .beta.-receptor blocking activity of 2-(p-nitrophenyl)-4-isopropylmorpholine A. Balsamo, Crotti, B. Macchia, F. Macchia, M. Del Tacca, and L. Mazzanti pp 224 - 227; DOI: 10.1021/jm00261a012 |
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Comparative study of the inhibitory activity of clofibrate and related analogs on lipoprotein lipase in vitro Thomas F. Whayne and Donald T. Witiak pp 228 - 231; DOI: 10.1021/jm00261a013 |
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cis- and trans-2-Mercaptocyclobutylamines, their benzylmercapto analogs, and aminomethyl homologs. Influence on bradykinin-induced contraction of the guinea pig ileum Donald T. Witiak, Birandra K. Sinha, Robert R. Ruffolo, and Popat N. Patil pp 232 - 235; DOI: 10.1021/jm00261a014 |
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Synthesis and biological activity of some carbocyclic analogs of muscarine Kurt G. R. Sundelin, R. A. Wiley, Richard S. Givens, and Don R. Rademacher pp 235 - 239; DOI: 10.1021/jm00261a015 |
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Bis-basic-substituted polycyclic aromatic compounds. New class of antiviral agents. 1. Bisalkamine esters of fluorenone-, fluorenol-, and fluorenedicarboxylic acids Arthur D. Sill, William L. Albrecht, Edwin R. Andrews, Robert W. Fleming, Stephen W. Horgan, Edward McC. Roberts, and F. William Sweet pp 240 - 245; DOI: 10.1021/jm00261a016 |
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Synthesis and cholinergic activity of some structural analogs of pilocarpine Ronald F. Borne, Hassan Y. Aboul-Enein, I. W. Waters, and Jennifer Hicks pp 245 - 247; DOI: 10.1021/jm00261a017 |
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Insect sex attractants. 13. Isolation, identification, and synthesis of sex pheromones of the male Mediterranean fruit fly Martin Jacobson, Kiichi Ohinata, Derrell L. Chambers, William A. Jones, and Martin S. Fujimoto pp 248 - 251; DOI: 10.1021/jm00261a018 |
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Synthesis and antiinflammatory activity of some 2,2-dimethyl-1,2-dihydroquinolines Robert D. Dillard, Donald E. Pavey, and Don N. Benslay pp 251 - 253; DOI: 10.1021/jm00261a019 |
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Derivatives of 3,4-dihydro-1(2H)-naphthalenone as .beta.-adrenergic blocking agents. 2. Aromatic-substituted analogs of bunolol Charles F. Schwender, Russell E. Pike, and John Shavel pp 254 - 257; DOI: 10.1021/jm00261a020 |
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Preparation of some 7-oxaandrostane derivatives Robert W. Guthrie, Alfred Boris, John G. Mullin, Francis A. Mennona, and Richard W. Kierstead pp 257 - 262; DOI: 10.1021/jm00261a021 |
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Aromatic esters which inhibit plasmin or thrombin by formation of relatively stable acyl enzymes George Glover, Chih-Cheng Wang, and Elliott Shaw pp 262 - 266; DOI: 10.1021/jm00261a022 |
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Absolute configuration of .alpha.-methyldopamine formed metabolically from .alpha.-methyldopa in man Kent S. Marshall and Neal Castagnoli pp 266 - 270; DOI: 10.1021/jm00261a023 |
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Ring D bridged steroid analogs. 11. High Clauberg activity of 19-nor-14.alpha.,17.alpha.-ethano-4-pregnene-3,20-dione A. J. Solo and J. N. Kapoor pp 270 - 273; DOI: 10.1021/jm00261a024 |
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Tyrosyl transfer ribonucleic acid synthetase from Escherichia coli B. Analysis of tyrosine and adenosine 5'-triphosphate binding sites Daniel V. Santi and Van A. Pena pp 273 - 280; DOI: 10.1021/jm00261a025 |
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Synthesis of a proposed pepsitensin Antonio C. M. Paiva, Therezinha B. Paiva, and Maria E. Miyamoto pp 280 - 281; DOI: 10.1021/jm00261a026 |
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Antimicrobials. New nitrofuran derivatives Etienne Szarvasi, Louis Fontaine, and Annie Betbeder-Matibet pp 281 - 287; DOI: 10.1021/jm00261a027 |
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Quaternary aminooxy congeners of acetyl .gamma.-homocholine Joseph G. Cannon, Patrick J. Mulligan, John E. Garst, John Paul Long, and Sharon Heintz pp 287 - 289; DOI: 10.1021/jm00261a028 |
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Improved synthesis of DL-alanosine Calley N. Eaton, George H. Denny, Malcolm A. Ryder, Manuel G. Ly, and Robert D. Babson pp 289 - 290; DOI: 10.1021/jm00261a029 |
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N6-(Dimethylamino)methylene derivative of 9-.beta.-D-arabinofuranosyladenine as an antiviral agent Stephen Hanessian pp 290 - 292; DOI: 10.1021/jm00261a030 |
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Synthesis of potential anticancer agents. Preparation of some 1-deazapurines and pyrimidines Carroll Temple, Buford H. Smith, Robert D. Elliott, and John A. Montgomery pp 292 - 294; DOI: 10.1021/jm00261a031 |
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Preparation and biological activity of various 3-deazapyrimidines and related nucleosides A. Bloch, G. Dutschman, Bruce L. Currie, Roland K. Robins, and Morris J. Robins pp 294 - 297; DOI: 10.1021/jm00261a032 |
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Synthesis and anticoccidial activity of 3-fluoro-5-chloro- and -bromo-2,6-dimethyl-4-pyridinol Lowell D. Markley and Michael K. Eckman pp 297 - 298; DOI: 10.1021/jm00261a033 |
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Antitumor agents. 4. Cytotoxicity and in vivo activity of helenalin esters and related derivatives Kuo-Hsiung Lee, Ronald Meck, Claude Piantadosi, and Eng-Shang Huang pp 299 - 301; DOI: 10.1021/jm00261a034 |
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Syntheses of heterocyclic compounds. 509. Syntheses of analgesics. 34. Synthesis of 3-hydroxy-N-cyclopropylmethyl-9-azamorphinan Tetsuji Kametani, Kazuo Kigasawa, Mineharu Hiiragi, Nagatoshi Wagatsuma, Tsuneo Uryu, and Kunio Araki pp 301 - 303; DOI: 10.1021/jm00261a035 |
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Synthesis of 6-(.alpha.-hydroxy-.beta.-N,N-dialkylaminoethyl)phenanthridines as potential antimalarials Chester W. Muth, Bhabatosh Bhattacharya, Robert L. Mahaffey, and Howard L. Minigh pp 303 - 305; DOI: 10.1021/jm00261a036 |
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Metabolism of acetylmethadol. Sensitive assay for noracetylmethadol and the identification of a new active metabolite Ruth E. Billings, Richard Booher, Stephen Smits, Albert Pohland, and Robert E. McMahon pp 305 - 306; DOI: 10.1021/jm00261a037 |
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Thyromimetic activity of 3,5,3'-trimethyl-L-thyronine Eugene C. Jorgensen and Paul Block pp 306 - 307; DOI: 10.1021/jm00261a038 |
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Book Reviews pp 307 - 308; DOI: 10.1021/jm00261a600 |
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Antiarrhythmic agents. Synthesis and biological activity of some tetrazole and oxadiazole analogs of 4-dialkylamino-2,2-diarylbutyramides Gilbert W. Adelstein pp 309 - 312; DOI: 10.1021/jm00262a001 |
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Nitrofuryltriazole derivatives as potential urinary tract antibacterial agents Eva B. Akerblom and Dag E. S. Campbell pp 312 - 319; DOI: 10.1021/jm00262a002 |
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Antiradiation agents. Substituted 2-pyridyloxy and 2-quinolyloxy derivatives of S-2-(alkylamino)ethyl hydrogen thiosulfates and 3-alkylthiazolidines and substituted 2-pyridyloxy derivatives of 2-(alkylamino)ethanethiols and corresponding disulfides Roger D. Westland, Richard A. Cooley, Joyce L. Holmes, Jean S. Hong, May H. Lin, and Martin L. Zwiesler pp 319 - 327; DOI: 10.1021/jm00262a003 |
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Antiradiation agents. 3-[(Alkylthio)alkyl]thiazolidines and substituted 2-{[(3-thiazolidinyl)alkyl]thio}pyridines and -quinolines Roger D. Westland, May H. Lin, Richard A. Cooley, and Martin L. Zwisler pp 328 - 331; DOI: 10.1021/jm00262a004 |
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Synthesis and hypotensive properties of tetrahydroisoquinolines Ian W. Mathison, Kathleen C. Fowler, Phillip H. Morgan, Richard R. Tidwell, Elizabeth R. Peters, Norbert J. Wojciechowski, James W. Lawson, and Frances K. Hetzer pp 332 - 336; DOI: 10.1021/jm00262a005 |
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Antimalarials. 2. Dihydro-1,3-oxazinoquinolines and dihydro-1,3-pyridobenzoxazines L. C. March, W. A. Romanchick, G. S. Bajwa, and M. M. Joullie pp 337 - 342; DOI: 10.1021/jm00262a006 |
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3,4-Dihydroisocarbostyril and 1,2,3,4-tetrahydroisoquinoline derivatives of ephedrine Donald L. Trepanier and Shyam Sunder pp 342 - 347; DOI: 10.1021/jm00262a007 |
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Antiparasitic nitroimidazoles. 3. Synthesis of 2-(4-carboxystyryl)-5-nitro-1-vinylimidazole and related compounds William J. Ross, William B. Jamieson, and Max C. McCowen pp 347 - 352; DOI: 10.1021/jm00262a008 |
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Isolation, x-ray analysis, and synthesis of a metabolite of (-)-3-hydroxy-N-allylmorphinan John F. Blount, Erno Mohacsi, and Floie M. Vane pp 352 - 355; DOI: 10.1021/jm00262a009 |
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Syntheses of actinomycin and analogs. 9. Synthesis of acetinomycin D lactam, [1',1'-bis(L-threo-.alpha.,.beta.-diaminobutyric acid)]actinomycin D Eric Atherton, Ravindra P. Patel, Yoshimoto Sano, and Johannes Meienhofer pp 355 - 358; DOI: 10.1021/jm00262a010 |
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Platelet aggregation inhibitors. 4. N6-Substituted adenosines Kiyomi Kikugawa, Kazuhiro Iizuka, and Motonobu Ichino pp 358 - 364; DOI: 10.1021/jm00262a011 |
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Nitrosaminopurines and nucleosides, synthesis and biological activity A. Giner-Sorolla, J. Longley-Cook, M. McCravey, George Bosworth Brown, and J. H. Burchenal pp 365 - 369; DOI: 10.1021/jm00262a012 |
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Synthesis and biological activity of the hypothalamic LH- and FSH-releasing decapeptide George R. Flouret, William H. Arnold, J. Wayne Cole, Ronald L. Morgan, Wilfrid F. White, Marc T. Hedlund, and Riemond H. Rippel pp 369 - 373; DOI: 10.1021/jm00262a013 |
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Synthesis and biological evaluation of LH- and FSH-releasing hormone and its analogs Noboru Yanaihara, Chizuko Yanaihara, Masanori Sakagami, Kazuyasu Tsuji, Tadashi Hashimoto, Toshio Kaneko, Hiroshi Oka, Andrew V. Schally, Akira Arimura, and Tommie W. Redding pp 373 - 377; DOI: 10.1021/jm00262a014 |
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Catechol O-methyltransferase. 1. Kinetics of tropolone inhibition Ronald T. Borchardt pp 377 - 382; DOI: 10.1021/jm00262a015 |
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Catechol O-methyltransferase. 2. In vitro inhibition by substituted 8-hydroxyquinolines Ronald T. Borchardt pp 382 - 387; DOI: 10.1021/jm00262a016 |
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Catechol O-methyltransferase. 3. Mechanism of pyridoxal 5'-phosphate inhibition Ronald T. Borchardt pp 387 - 391; DOI: 10.1021/jm00262a017 |
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Synthesis of new bis(1-aziridinyl) phosphinate alkylating agents containing O-phenyl N-phenylcarbamate side chains Y. Y. Hsiao and T. J. Bardos pp 391 - 394; DOI: 10.1021/jm00262a018 |
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local anesthetic azabicyclo-N-alkylanilides Willem F. M. Van Bever, Alfons G. Knaeps, Johan J. M. Willems, Bert K. F. Hermans, and Paul A. J. Janssen pp 394 - 397; DOI: 10.1021/jm00262a019 |
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Chemical transformations of antibiotic X-537A and their effect on antibacterial activity John W. Westley, Eugene P. Oliveto, Julius Berger, Ralph H. Evans, Richard Glass, Arthur Stempel, Voldemar Toome, and Thomas Williams pp 397 - 403; DOI: 10.1021/jm00262a020 |
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Substituted tetrahydrofurfurylamines as potential antidepresaants I. Monkovic, Y. G. Perron, R. Martel, W. J. Simpson, and J. A. Gylys pp 403 - 407; DOI: 10.1021/jm00262a021 |
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Amidines. 4. Synthesis of tricyclic guanidines related to 1,2,3,5-tetrahydroimidazo[2,1-b]quinazoline, a new antihypertensive agent Timothy Jen, Paul Bender, Helen Van Hoeven, Barbara Dienel, and Bernard Loev pp 407 - 411; DOI: 10.1021/jm00262a022 |
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Radioprotective thiazolidines from .beta.-keto esters Patrick S. Farmer, Chun-Cheung Leung, and Edmund M. K. Lui pp 411 - 413; DOI: 10.1021/jm00262a023 |
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Naphthothiophenes. 2. Benzo[1,2-b:4,3-b']dithiophenemethanols as isosteres of naphthothiophenes Bijan P. Das and David W. Boykin pp 413 - 415; DOI: 10.1021/jm00262a024 |
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Specificity of antibodies produced by linear antigenic polypeptides of a known primary structure. Synthesis and use of poly(L-tyrosyl-L-aspartyl-L-alanylglycyl)glycine methyl ester Brian J. Johnson and Charles Cheng pp 415 - 416; DOI: 10.1021/jm00262a025 |
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Synthesis of 3,4-dihydroxy-5-fluoro-DL-phenylalanine and 3,4-dihydroxy-5-[fluorine-18]fluoro-DL-phenylalanine Gunter Firnau, Claude Nahmias, and Stephen Garnett pp 416 - 418; DOI: 10.1021/jm00262a026 |
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Alkaloids in mammalian tissues. 3. Condensation of L-tryptophan and L-5-hydroxytryptophan with formaldehyde and acetaldehyde Arnold Brossi, Antonino Focella, and Sidney Teitel pp 418 - 420; DOI: 10.1021/jm00262a027 |
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Convenient, general procedure for preparing specifically tritium-labeled amines. Synthesis of tritium-labeled meperidine hydrochloride P. S. Portoghese and D. L. Larson pp 420 - 421; DOI: 10.1021/jm00262a028 |
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Anticancer compounds. Further analogs of 1-(4-dimethylaminobenzylidene)indene Carl T. Bahner, Norma H. Bingham, David H. Brotherton, Jane Cline, Dan Darby, Harry D. Harmon, Lydia M. Rives, Bill L. Stump, and L. Watson pp 421 - 425; DOI: 10.1021/jm00262a029 |
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N-Alkylaminocarbazoles as potential anticonvulsant and diuretic agents Aboo Shoeb, Falak Anwer, Randhir S. Kapil, Satya P. Popli, Prithvi Dua, and Bhola N. Dhawan pp 425 - 427; DOI: 10.1021/jm00262a030 |
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Attempted latentiation of 2-acetamidoethanethiol with .alpha.,.beta.-unsaturated acids Pramod K. Srivastava and Lamar Field pp 428 - 429; DOI: 10.1021/jm00262a031 |
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Synthesis and biological effects of 13-dehydro derivatives of natural prostaglandin F2.alpha. and E2 and their 15-epienantiomers Josef Fried and C. H. Lin pp 429 - 430; DOI: 10.1021/jm00262a032 |
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Book Reviews pp 431 - 432; DOI: 10.1021/jm00262a600 |
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2,6-Dihydroxybenzoic acid anilides as fasciolicides D. Duewel and H. Metzger pp 433 - 436; DOI: 10.1021/jm00263a001 |
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2,6-Dihydroxybenzoic acid anilides active against liver flukes. Hansch analysis E. Druckrey and H. Metzger pp 436 - 439; DOI: 10.1021/jm00263a002 |
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Stereospecificity of closely related compounds which block postganglionic acetylcholine receptors in the guinea-pig ileum R. B. Barlow, Fiona M. Franks, and J. D. M. Pearson pp 439 - 446; DOI: 10.1021/jm00263a003 |
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Linear free energy relations in the hydrolysis of some inhibitors of acetylcholinesterase Yacov Ashani, Stephen L. Snyder, and Irwin B. Wilson pp 446 - 450; DOI: 10.1021/jm00263a004 |
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Synthesis of some N-substituted eleostearic acid hydrazides as potential monoamine oxidase inhibitors Song Y. Hsu, Chian L. Huang, and Irving W. Waters pp 450 - 452; DOI: 10.1021/jm00263a005 |
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Irreversible enzyme inhibitors. 198. Diaminodihydro-s-triazines and diaminopyrimidines bearing substituted (ureidomethyl)phenyl substituents as reversible inhibitors of dihydrofolate reductase Wallace T. Ashton, Larry L. Kirk, and B. R. Baker pp 453 - 456; DOI: 10.1021/jm00263a006 |
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Specificity of inhibition of adenosine deaminase by trialcohols derived from nucleosides Ralph R. Rossi and Leon M. Lerner pp 457 - 460; DOI: 10.1021/jm00263a007 |
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Analogs of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Specificity of the S-adenosylhomocysteine binding site James K. Coward and Edwin P. Slisz pp 460 - 463; DOI: 10.1021/jm00263a008 |
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Solid-phase synthesis and some pharmacological properties of 4-threonine analogs of vasopressins and vasotocin and of argininevasopressin and arginine-vasotocin Maurice Manning, Esther J. Coy, Wilbur H. Sawyer, and Margot Acosta pp 463 - 466; DOI: 10.1021/jm00263a009 |
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Angiotensin II analogs. 10. Stereochemical factors in the 5 position influencing pressor activity Eugene C. Jorgensen, Graham C. Windridge, and Thomas C. Lee pp 467 - 469; DOI: 10.1021/jm00263a010 |
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Solution conformations of histamine and some related derivatives Norman S. Ham, Alan F. Casy, and Robin R. Ison pp 470 - 475; DOI: 10.1021/jm00263a011 |
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New chiral reagent for the determination of enantiomeric purity and absolute configuration of certain substituted .beta.-arylethylamines Lance R. Pohl and William F. Trager pp 475 - 479; DOI: 10.1021/jm00263a012 |
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Asymmetric synthesis of psychotomimetic phenylisopropylamines David E. Nichols, Charles F. Barfknecht, David B. Rusterholz, Frederick Benington, and Richard D. Morin pp 480 - 483; DOI: 10.1021/jm00263a013 |
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Binding of certain nonsteroid antiinflammatory agents and uricosuric agents to human serum albumin William J. Dunn pp 484 - 486; DOI: 10.1021/jm00263a014 |
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Synthesis and antiinflammatory activities of (.alpha.-cyclopropyl-p-tolyl)acetic acid and related compounds G. Rovnyak, P. A. Diassi, S. D. Levine, and J. T. Sheehan pp 487 - 490; DOI: 10.1021/jm00263a015 |
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4- and 5-Aryl-1-naphthaleneacetic acids as antiinflammatory agents James S. Kaltenbronn pp 490 - 493; DOI: 10.1021/jm00263a016 |
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Potent antiinflammatory N-heterocyclic 3-carboxamides of 4-hydroxy-2-methyl-2H-1,2-benzothiazine 1,1-dioxide Joseph G. Lombardino, Edward H. Wiseman, and Josephine Chiaini pp 493 - 496; DOI: 10.1021/jm00263a017 |
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Effects of a series of new synthetic high polymers on cancer metastases P. Ferruti, F. Danusso, G. Franchi, N. Polentarutti, and S. Garattini pp 496 - 499; DOI: 10.1021/jm00263a018 |
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N-Hydroxylation of p-acetophenetidide as a factor in nephrotoxicity Ian C. Calder, Michael J. Creek, Patrick J. Williams, Christopher C. Funder, Charles R. Green, Kathryn N. Ham, and John D. Tange pp 499 - 502; DOI: 10.1021/jm00263a019 |
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Metabolic conversion of benzo[a]pyrene by Syrian hamster liver microsomes and binding of metabolites to deoxyribonucleic acid A. Borgen, H. Darvey, N. Castagnoli, T. T. Crocker, R. E. Rasmussen, and I. Y. Wang pp 502 - 506; DOI: 10.1021/jm00263a020 |
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Stereochemical analogs of a muscarinic, ganglionic stimulant. cis- and trans-4-[N-(3-Chlorophenyl)carbamoyloxy]-2-butenyltrimethylammonium iodides W. L. Nelson, D. S. Freeman, P. D. Wilkinson, and F. F. Vincenzi pp 506 - 510; DOI: 10.1021/jm00263a021 |
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2-Amino-5-substituted oxazolines and intermediates as potential anorectants Edward R. Freiter, Abdulmunien H. Abdallah, and Stanley J. Strycker pp 510 - 512; DOI: 10.1021/jm00263a022 |
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3,5-Dialkyl-4-(phthalimidomethyl)isoxazoles, pyrazoles, and isothiazoles. Novel antiandrogens John W. Scott and Alfred Boris pp 512 - 516; DOI: 10.1021/jm00263a023 |
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Selectivity in new .beta.-adrenergic blocking agents. (3-Amino-2-hydroxypropoxy)benzamides G. Shtacher, M. Erez, and S. Cohen pp 516 - 519; DOI: 10.1021/jm00263a024 |
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Pyrido[3,2-g]pteridines. 2. Synthesis and growth-inhibitory evaluation of some 10-substituted 3H,10H-2,4-dioxopyrido[3,2-g]pteridines (9-azaisoalloxazines) Mervyn Israel and Nilly Tirosh pp 520 - 524; DOI: 10.1021/jm00263a025 |
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Pyridine nucleosides related to 5-fluorouracil and thymine Stephen Nesnow, Teruko Miyazaki, Tasneem Khwaja, Rich B. Meyer, and Charles Heidelberger pp 524 - 528; DOI: 10.1021/jm00263a026 |
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Antimalarials. 9. .alpha.-(2-Piperidyl)-4-quinolinemethanols carrying 2-aroxy and 2-(p-chloroanilino) groups Charles R. Wetzel, James R. Shanklin, and Robert E. Lutz pp 528 - 532; DOI: 10.1021/jm00263a027 |
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Emetic activity of reduced lysergamides Fatima N. Johnson, Istvan E. Ary, David G. Teiger, and Ronald J. Kassel pp 532 - 537; DOI: 10.1021/jm00263a028 |
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6-Substituted 5-chloro-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-ones with hypotensive activity James H. Jones, Wilbur J. Holtz, and Edward J. Cragoe pp 537 - 542; DOI: 10.1021/jm00263a029 |
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Total synthesis of the macrolide, (R,S)-zearalanone Richard N. Hurd and D. H. Shah pp 543 - 545; DOI: 10.1021/jm00263a030 |
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Synthetic luteinizing hormone releasing factor analogs. Series of short-chain amide LRF homologs converging to the amino terminus J. Rivier, W. Vale, R. Burgus, N. Ling, M. Amoss, R. Blackwell, and R. Guillemin pp 545 - 549; DOI: 10.1021/jm00263a031 |
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Synthesis and properties of fluorine-containing heterocyclic compounds. 8. .alpha.-(2-Pyridyl)- and .alpha.-(2-piperidyl)-2-(trifluoromethyl)-4-azaphenanthrenemethanols M. Loy and M. M. Joullie pp 549 - 552; DOI: 10.1021/jm00263a032 |
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Narcotic antagonists. 1. Isomeric sulfate and acetate esters of naloxone (N-allylnoroxymorphone) Charles Linder and Jack Fishman pp 553 - 556; DOI: 10.1021/jm00263a033 |
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Narcotic antagonists. 2. Preparation and biological stability of naloxone-7,8-3H Jack Fishman, Mary Lou Cotter, and Baiba I. Norton pp 556 - 557; DOI: 10.1021/jm00263a034 |
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New 5-substituted 1-alkyl-2-nitroimidazoles Bruno Cavalleri, Roberto Ballotta, Vittorio Arioli, and Giancarlo Lancini pp 557 - 560; DOI: 10.1021/jm00263a035 |
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Agents acting on the central nervous system. 15. 2-Substituted 1,2,3,4,6,7,12,12a-octahydropyrazino [2',1':6,1]pyrido[3,4-b]indoles. New class of central nervous system depressants Anil K. Saxena, Padam C. Jain, Nitya Anand, and P. R. Dua pp 560 - 564; DOI: 10.1021/jm00263a036 |
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Epimeric forms of quaternary derivatives of atropine R. B. Barlow, Margaret Harrison, R. R. Ison, and J. D. M. Pearson pp 564 - 566; DOI: 10.1021/jm00263a037 |
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Nitrones. 6. .alpha.-(5-Nitroimidazol-2-yl)-N-substituted nitrones Ronald E. Bambury, C. Michael Lutz, Laird F. Miller, Hyun K. Kim, and H. W. Ritter pp 566 - 568; DOI: 10.1021/jm00263a038 |
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7-Acetylthioetiojervanes, new antialdosterone agents William F. Johns and Lorenz M. Hofmann pp 568 - 570; DOI: 10.1021/jm00263a039 |
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Synthesis of nucleoside 5'-carbamates Wayne C. Fleming, William W. Lee, and David W. Henry pp 570 - 571; DOI: 10.1021/jm00263a040 |
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Hypocholesterolemic agents. 10. Synthesis of some model azacholanic acids as potential regulators of steroid biosynthesis and metabolism D. L. Venton, F. Kohen, and R. E. Counsell pp 571 - 573; DOI: 10.1021/jm00263a041 |
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Polyethylene glycol derivatives of procaine Ben-Zion Weiner and Albert Zilkha pp 573 - 574; DOI: 10.1021/jm00263a042 |
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Nitro analogs of pyoluteorins Colin G. Hughes and Alun H. Rees pp 574 - 576; DOI: 10.1021/jm00263a043 |
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Hydroxylamine derivatives as potential inhibitors of nucleic acid synthesis John B. Hynes, Glen R. Gale, Loretta M. Atkins, David M. Cline, and Kenneth F. Hill pp 576 - 578; DOI: 10.1021/jm00263a044 |
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Utility of the Topliss schemes for analog synthesis Yvonne C. Martin and William J. Dunn pp 578 - 579; DOI: 10.1021/jm00263a045 |
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Inhibition of thymidine kinase from Walker 256 carcinoma by thymidine analogs John P. Neenan and Wolfgang Rohde pp 580 - 581; DOI: 10.1021/jm00263a046 |
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Catechol O-methyltransferase. 4. In vitro inhibition by 3-hydroxy-4-pyrones, 3-hydroxy-2-pyridones, and 3-hydroxy-4-pyridones Ronald T. Borchardt pp 581 - 583; DOI: 10.1021/jm00263a047 |
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New method for nitrosation of proline and related sec-.alpha.-amino acids to N-nitrosamino acids with possible oncogenic activity H. T. Nagasawa, P. S. Fraser, and D. L. Yuzon pp 583 - 585; DOI: 10.1021/jm00263a048 |
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Derivatives of 3,4-dihydro-1(2H)-naphthalenone as .beta.-adrenergic blocking agents. 3. Carbonyl-containing analogs of bunolol Charles F. Schwender, Russell E. Pike, Brooks R. Sunday, and John Shavel pp 585 - 588; DOI: 10.1021/jm00263a049 |
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Book Reviews pp 588 - 588; DOI: 10.1021/jm00263a600 |
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Stereochemical studies on medicinal agents. 15. Absolute configurations and analgetic potecies of enantiomeric diastereomers of 3-allyl-1-methyl-4-phenyl-4-propionoxypiperidine Kevin H. Bell and Philip S. Portoghese pp 589 - 591; DOI: 10.1021/jm00264a001 |
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Synthesis, stereochemistry and analgesic activities of diastereoisomeric esters of 3-allyl-4-phenyl-4-piperidinol M. A. Iorio, G. Damia, and A. F. Casy pp 592 - 595; DOI: 10.1021/jm00264a002 |
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Bridged aminotetralins as novel potent analgesic substances Meier E. Freed, John R. Potoski, Elisabeth H. Freed, George L. Conklin, and Jerry L. Malis pp 595 - 599; DOI: 10.1021/jm00264a003 |
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Metabolism of dimethoxymethylphenobarbital in mice. Relation between brain phenobarbital levels and anticonvulsant activity Richard L. Rapport and Harvey J. Kupferberg pp 599 - 602; DOI: 10.1021/jm00264a004 |
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Anticonvulsants. 3. Phenobarbital and mephobarbital derivatives Julius A. Vida, Mary L. Hooker, and John F. Reinhard pp 602 - 605; DOI: 10.1021/jm00264a005 |
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Effect of phenobarbital treatment on the stereochemistry of the in vitro metabolism of ethylbenzene G. A. Maylin, M. J. Cooper, and M. W. Anders pp 606 - 610; DOI: 10.1021/jm00264a006 |
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Conformation of histamine derivatives. 1. Application of molecular orbital calculations and nuclear magnetic resonance spectroscopy C. R. Ganellin, E. S. Pepper, G. N. J. Port, and W. G. Richards pp 610 - 616; DOI: 10.1021/jm00264a007 |
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Conformation of histamine derivatives. 2. Molecular orbital calculations of preferred conformations in relation to dual receptor activity C. R. Ganellin, G. N. J. Port, and W. G. Richards pp 616 - 620; DOI: 10.1021/jm00264a008 |
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Conformation of histamine derivatives. 3. Relation between conformation and pharmacological activity C. R. Ganellin pp 620 - 623; DOI: 10.1021/jm00264a009 |
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Solid-phase synthesis of [2-isoleucine, 4-leucine]oxytocin and [2-phenylalanine, 4-leucine]oxytocin and some of their pharmacological properties Victor J. Hruby, Fugen Muscio, Charles M. Grogisky, Peter M. Gitu, Don Saba, and Walter Y. Chan pp 624 - 629; DOI: 10.1021/jm00264a010 |
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Synthesis and pharmacology of centrally acting dopamine derivatives and analogs in relation to Parkinson's disease Robert J. Borgman, Joseph J. McPhillips, Robert E. Stitzel, and Irving J. Goodman pp 630 - 633; DOI: 10.1021/jm00264a011 |
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Amidines. 5. Synthesis of pyrrolo[2,3,-b]isoquinoline imidazo[1,2-b]isoquinoline, pyrrolo[2,1-b]quinazoline, and 1,3-thiazino[2,3-b]quinazoline derivatives and related heterocycles as potential antihypertensive agents Timothy Jen, Barbara Dienel, Frederic Dowalo, Helene Van Hoeven, Paul Bender, and Bernard Loev pp 633 - 637; DOI: 10.1021/jm00264a012 |
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Chemistry and biology of vitamin B6. 31. Synthesis and physicochemical and biological properties of 6-halogen-substituted vitamin B6 analogs W. Korytnyk and S. C. Srivastava pp 638 - 642; DOI: 10.1021/jm00264a013 |
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Synthesis and biological activity of some imidazo[4,5-b]pyrazines and their ribonucleosides as purine analogs R. A. Sharma, M. Bobek, F. E. Cole, and A. Bloch pp 643 - 647; DOI: 10.1021/jm00264a014 |
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Preparation of 17a-acetoxy-7-oxaprogesterone Ronald A. LeMahieu, Alfred Boris, Mathew Carson, Robert W. Guthrie, and Richard W. Kierstead pp 647 - 649; DOI: 10.1021/jm00264a015 |
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19-Norprogestins synthesis and biological activity of 6-chloro-16-methylene-17a-hydroxy-19-nor-4,6-pregnadiene-3,20-dione 17-acetate E. L. Shapiro, L. Weber, G. Teutsch, H. Harris, R. Neri, and H. L. Herzog pp 649 - 654; DOI: 10.1021/jm00264a016 |
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Study of structure-activity relation of a series of diphenylaminopropanols by factor analysis Myra L. Weiner and Paul H. Weiner pp 655 - 661; DOI: 10.1021/jm00264a017 |
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Structure-activity correlations of antimalarial compounds. 2. Phenanthreneaminoalkylcarbinol antimalarials Paul N. Craig and Corwin H. Hansch pp 661 - 667; DOI: 10.1021/jm00264a018 |
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Compounds affecting the central nervous system. 3. 3.beta.-Phenyltropan-2-ols Sol J. Daum, Mario D. Aceto, and Robert L. Clarke pp 667 - 670; DOI: 10.1021/jm00264a019 |
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3-Amino-4-halosydnone imines. New type of antihypertensive agent Manfred Goetz, Karl Grozinger, and James T. Oliver pp 671 - 673; DOI: 10.1021/jm00264a020 |
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Potential antitumor agents. 13. Bisquaternary salts G. J. Atwell and B. F. Cain pp 673 - 678; DOI: 10.1021/jm00264a021 |
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Hypoglycemic cycloalkyl lactamimides J. Martin Grisar, George P. Claxton, Albert A. Carr, and Norbert L. Wiech pp 679 - 683; DOI: 10.1021/jm00264a022 |
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Potential organ or tumor imaging agents. 11. Radioiodinated tyramines R. E. Counsell, T. D. Smith, V. V. Ranade, O. P. D. Noronha, and P. Desai pp 684 - 687; DOI: 10.1021/jm00264a023 |
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Substituted 3,4-pentadienyldiamines as inhibitors of platelet aggregation Charles H. Tilford, Robert D. MacKenzie, Thomas R. Blohm, and J. Martin Grisar pp 688 - 693; DOI: 10.1021/jm00264a024 |
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Quinazolines as inhibitors of dihydrofolate reductase. 1 Wallace T. Ashton, F. C. Walker, and John B. Hynes pp 694 - 697; DOI: 10.1021/jm00264a025 |
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Folic acid analogs. Modifications in the benzene-ring region. 3. Neohomofolic and neobishomofolic acids. Improved synthesis of folic acid and its analogs Eugene C. Roberts and Y. Fulmer Shealy pp 697 - 699; DOI: 10.1021/jm00264a026 |
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Oxime analogs of physostigmine J. N. Wells, J. N. Davisson, W. R. Campbell, S. Sangiah, and G. K. W. Yim pp 700 - 703; DOI: 10.1021/jm00264a027 |
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10,11-Dihydro-10,11-dihydroxy-5H-dibenz[b,f]azepine-5-carboxamide, a metabolite of carbamazepine isolated from human and rat urine K. M. Baker, J. Csetenyi, A. Frigerio, P. L. Morselli, F. Parravicini, and G. Pifferi pp 703 - 705; DOI: 10.1021/jm00264a028 |
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Nitrohistidines and nitrohistamines W. Tautz, S. Teitel, and A. Brossi pp 705 - 707; DOI: 10.1021/jm00264a029 |
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Spin-labeled analogs of local anesthetics Robert J. Gargiulo, Gregory J. Giotta, and Howard H. Wang pp 707 - 708; DOI: 10.1021/jm00264a030 |
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Potential antimicrobial furans William Hoyle, Gordon P. Roberts, and Otto Meth-Cohn pp 709 - 710; DOI: 10.1021/jm00264a031 |
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Di-.alpha.-[4-Isobutyl(cyclohexen-1-yl)]alkanoic acids and derivatives as fibrinolytic and thrombolytic compounds Michel Vincent, Georges Remond, Pierre Desnoyers, and Jacqueline Labaume pp 710 - 712; DOI: 10.1021/jm00264a032 |
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Synthesis of 5-trifluoromethyl-2'-deoxyuridine 5'-phosphate and 5-trifluoromethyl-2'-deoxyuridine 5'-triphosphate Peter V. Denenberg and Charles Heidelberger pp 712 - 714; DOI: 10.1021/jm00264a033 |
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Synthesis and carcinogenicity of compounds related to 6-hydroxymethylbenzo[a]pyrene R. K. Natarajan and J. W. Flesher pp 714 - 715; DOI: 10.1021/jm00264a034 |
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Potential antitumor agents. 7. 4'-diethyleneoxy derivatives of .alpha.-(N)-heterocyclic carboxaldehyde thiosemicarbazones Krishna C. Agrawal, Barbara A. Booth, and Alan C. Sartorelli pp 715 - 717; DOI: 10.1021/jm00264a035 |
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Carcinogenic activity of benzofuran and dibenzofuran analogs of p-dimethylaminoazobenzene Ellis V. Brown and Ray L. Coleman pp 717 - 718; DOI: 10.1021/jm00264a036 |
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Stereoselectivity of cholinergic activity in a series of 1,3-dioxolanes K. J. Chang and D. J. Triggle pp 718 - 720; DOI: 10.1021/jm00264a037 |
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Analgetic-antiinflammatory activity of prenyl derivatives of basic naphthylalkylnitriles and naphthylalkylamides chemically related to naphthypramide Gianfranco Pala, Arturo Donetti, Bruno Lumachi, and Graziano Bonardi pp 720 - 723; DOI: 10.1021/jm00264a038 |
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Effect of the substituent at C-6 on the biological activity of 2,4-diamino-5-(1-adamantyl) pyrimidines J. P. Jonak, L. H. Mead, Y. K. Ho, and S. F. Zakrzewski pp 724 - 725; DOI: 10.1021/jm00264a039 |
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Phenol-piperazine adducts showing anthelmintic properties Richard Rips, Gabrielle Boschi, Minh Chau Trinh, and Raymond Cavier pp 725 - 728; DOI: 10.1021/jm00264a040 |
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Molecular orbital calculations of furfuryltrimethylammonium James W. Crow pp 728 - 729; DOI: 10.1021/jm00264a041 |
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Silyl ether precursor-type insect repellents Daniel D. Garner and Lorrin R. Garson pp 729 - 732; DOI: 10.1021/jm00264a042 |
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1,6-bis(N5-m-Trifluoromethylphenyl-N1-biguanido)hexane and related analogs of chlorhexidine as inhibitors of dental plaque Victor D. Warner, Dale B. Mirth, Samuel S. Turesky, and Irving Glickman pp 732 - 733; DOI: 10.1021/jm00264a043 |
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Synthesis and pharmacology of position 6 analogs of angiotensin II Richard J. Freer and John Morrow Stewart pp 733 - 735; DOI: 10.1021/jm00264a044 |
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L-5-Oxo-2-pyrrolidinecarboxamides from phenethylamines Lewis A. Walter, Robert J. Gyurik, Wei Chang, and Allen Barnett pp 735 - 736; DOI: 10.1021/jm00264a045 |
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Antifertility activity of some .beta.-amino alcohols Duane F. Morrow, Porter C. Johnson, Houshang Torabi, David Williams, Donald L. Wedding, Joe W. Craig, Robert F. Majewski, John P. Braselton, and Duane G. Gallo pp 736 - 739; DOI: 10.1021/jm00264a046 |
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Local anesthetics. Alkylthioalkyl- and alkylsulfinylalkylaminoacylanilides George H. Kronberg, Richard S. Leard, and Bertil H. Takman pp 739 - 743; DOI: 10.1021/jm00264a047 |
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Book Reviews pp 743 - 744; DOI: 10.1021/jm00264a600 |
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Model building in structure-activity relations. Reexamination of adrenergic blocking activity of .beta.-halo-.beta.-arylalkylamines Stefan H. Unger and Corwin Hansch pp 745 - 749; DOI: 10.1021/jm00265a001 |
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Synthesis and structure-activity relations of fibrinolytic 1,.omega.-diphenyl-1,.omega.-alkanediamines Leonard J. Fliedner, Melvyn J. Myers, Joseph M. Schor, and Irwin J. Pachter pp 749 - 754; DOI: 10.1021/jm00265a002 |
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Nucleic acids. 14. Synthesis and antiviral activity of some 5'-esters of 9-.beta.-D-arabinofuranosyladenine (ara-A) Harold E. Renis, Duant T. Gish, Barbara A. Court, Emerson E. Eidson, and William J. Wechter pp 754 - 757; DOI: 10.1021/jm00265a003 |
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Synthesis and antiinflammatory evaluation of certain 5-alkoxy-2,7-dialkyltryptamines John F. Poletto, George R. Allen, Adolf E. Sloboda, and Martin J. Weiss pp 757 - 765; DOI: 10.1021/jm00265a004 |
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Synthesis and biological activities of 7-ethyl-8-chloro-10-(1,-D-ribityl)isoalloxazine and 7-chloro-8-ethyl-10-1(1'-D-ribityl)isoalloxazine, analogs of riboflavine John Patrick Lambooy and John Peter Lambooy pp 765 - 770; DOI: 10.1021/jm00265a005 |
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Cycloalkanones. 2. Synthesis and biological activity of .alpha.,.alpha.'-dibenzylcycloalkanones Claude Piantadosi, Iris H. Hall, John L. Irvine, and Gerald L. Carlson pp 770 - 775; DOI: 10.1021/jm00265a006 |
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4-[3-(Dimethylamino)propyl]-3,4-dihydro-2-(1-hydroxyethyl)-3-phenyl-2H-1,4-benzothiazine and related compounds. New class of antiinflammatory agents John Krapcho and Chester F. Turk pp 776 - 779; DOI: 10.1021/jm00265a007 |
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Antiinflammatory activities of 2-acetyl- and 2-(1-hydroxyethyl)-4-[3-(dimethylamino)propyl]-3,4-dihydro-3-phenyl-2H-1,4-benzothiazine Robert C. Millonig, Marvin B. Goldlust, William E. Maguire, Bernard Rubin, Ernst Schulze, Robert J. Wojnar, A. Robert Turkheimer, Wiliam F. Schreiber, and Russell J. Brittain pp 780 - 782; DOI: 10.1021/jm00265a008 |
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Synthetic antidiarrheal agents. 2,2-Diphenyl-4-(4'-aryl-4'-hydroxypiperidino)butyramides Raymond A. Stokbroekx, Jan Vandenberk, Albert H. M. T. Van Heertum, Gerard M. L. W. Van Laar, Marcel J. M. C. Van der Aa, Willem F. M. Van Bever, and Paul A. J. Janssen pp 782 - 786; DOI: 10.1021/jm00265a009 |
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Cyclizing compounds. 3. Local anesthetic action of N-(.omega.-haloalkyl)-N-methylaminoaceto-2,6-xylidides Svante B. Ross, Rune Sandberg, Bengt A. Akerman, Karl E. Domeij, Goran Stening, and Soren Svensson pp 787 - 790; DOI: 10.1021/jm00265a010 |
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Structure-activity relations of three groups of uncouplers of oxidative phosphorylation. Salicylanilides, 2-trifluoromethylbenzimidazoles, and phenols Jan P. Tollenaere pp 791 - 796; DOI: 10.1021/jm00265a011 |
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Agents acting on the central nervous system. 19. (+-)-1-(o- and m-Alkanoylphenoxy)-3-(N4-arylpiperazinyl)propan-2-ols as local anesthetics, hypotensives, and tranquilizers Shri N. Rastogi, Nitya Anand, P. P. Gupta, and J. N. Sharma pp 797 - 804; DOI: 10.1021/jm00265a012 |
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Potential psychotomimetics. 2-Amino-1,2,3,4-tetrahydronaphthalene analogs C. F. Barfknecht, D. E. Nichols, D. B. Rusterholz, J. P. Long, J. A. Engelbrecht, J. M. Beaton, R. J. Bradley, and D. C. Dyer pp 804 - 808; DOI: 10.1021/jm00265a013 |
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Isoquinolines. 3. 3-Aminoisoquinoline derivatives with central nervous system depessant activity John L. Neumeyer, Klaus K. Weinhardt, Richard A. Carrano, and David H. McCurdy pp 808 - 813; DOI: 10.1021/jm00265a014 |
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Potential antifertility agents. 4. Biological properties of diastereoisomeric 4-aryl-2-methylcyclohexanecarboxylic acids and related compounds R. R. Crenshaw, George M. Luke, Thomas A. Jenks, Richard A. Partyka, Gabriel Bialy, and Max E. Bierwagen pp 813 - 823; DOI: 10.1021/jm00265a015 |
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2-Aminoadamantane-2-carboxylic acid, a rigid, achiral, tricyclic .alpha.-amino acid with transport inhibitory properties H. T. Nagasawa, J. A. Elberling, and F. N. Shirota pp 823 - 826; DOI: 10.1021/jm00265a016 |
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Analogs of luteinizing hormone-releasing hormone containing derivatives of phenylalanine in place of tyrosine David H. Coy, Esther J. Coy, and Andrew V. Schally pp 827 - 829; DOI: 10.1021/jm00265a017 |
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Factors that influence the antagonistic properties of angiotensin II antagonists M. C. Khosla, M. M. Hall, R. R. Smeby, and F. M. Bumpus pp 829 - 832; DOI: 10.1021/jm00265a018 |
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Uptake of androgen analogs by prostate tissue Yasuji Kasuya and Manfred E. Wolff pp 832 - 836; DOI: 10.1021/jm00265a019 |
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Solid-phase synthesis and some pharmacological properties of deamino-4-threonine analogs of the vasopressins and vasotocin and [deamino]arginine-vasotocin Maurice Manning, Esther J. Coy, Margot Acosta, and Wilbur H. Sawyer pp 836 - 839; DOI: 10.1021/jm00265a020 |
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3-(16.beta.-17.beta.-Dihydroxy-3-oxoandrost-4-en-17.alpha.-yl)propionic acid .gamma.-lactone, its preparation and antimineralocorticoid activity Leland J. Chinn and Lorenz M. Hofmann pp 839 - 843; DOI: 10.1021/jm00265a021 |
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Synthesis and some of the pharmacological properties of [4-leucine]-8-lysine-vasopressin and [1-deamino,4-leucine]-8-lysine-vasopressin Douglas F. Dyckes, Martha F. Ferger, Vincent Du Vigneaud, and W. Y. Chan pp 843 - 847; DOI: 10.1021/jm00265a022 |
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Trimethylammonium phenyl ketones. Actions on the cholinergic receptor and acetylcholinesterase Jorge A. Hasbun, Karen K. Barker, and Mathias P. Mertes pp 847 - 849; DOI: 10.1021/jm00265a023 |
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2,3-Disubstituted 1,6-naphthyridines as potential diuretic agents Edward M. Hawes, Dennis K. J. Gorecki, and Dennis D. Johnson pp 849 - 853; DOI: 10.1021/jm00265a024 |
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2-Azabicyclo[2.2.2.]octane derivatives as conformational analogs of local anesthetics Ronald F. Borne, C. Randall Clark, and John M. Holbrook pp 853 - 856; DOI: 10.1021/jm00265a025 |
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Relative potency of (-)- and (+-)-salbutamol on guinea pig tracheal tissue Clifford J. Hawkins and Gregory T. Klease pp 856 - 857; DOI: 10.1021/jm00265a026 |
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Synthesis of noformycin Guy D. Diana pp 857 - 859; DOI: 10.1021/jm00265a027 |
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Preparation and cardiovascular actions of a group of tetrahydroisoquinoline derivatives Allan P. Gray and Richard H. Shiley pp 859 - 861; DOI: 10.1021/jm00265a028 |
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Antiasthma agents. 1. 4-Oxo-4H-[1]benzothieno[3,2-b]pyran-2-carboxylic acid and 4-oxo-4H-[1]benzofuro[3,2-b]pyran-2-carboxylic acid John B. Wright and Herbert G. Johnson pp 861 - 862; DOI: 10.1021/jm00265a029 |
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Antiparasitic nitroimidazoles. 7. 4- and 5-Styrylnitroimidazoles William J. Ross and Alec Todd pp 863 - 865; DOI: 10.1021/jm00265a030 |
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Chemistry and biology of vitamin B6. 32. Selective modification of the .alpha.4 position of pyridoxol. 4-Vinyl analog of pyridoxal, a potent antagonist of vitamin B6 W. Korytnyk, G. B. Grindey, and B. Lachmann pp 865 - 867; DOI: 10.1021/jm00265a031 |
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Book Reviews pp 867 - 868; DOI: 10.1021/jm00265a600 |
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Pteridines. 2. New 6,7-disubstituted pteridines as potential antimalarial and antitumor agents A. Rosowsky, M. Chaykovsky, M. Lin, and E. J. Modest pp 869 - 875; DOI: 10.1021/jm00266a001 |
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2-Substituted cinchoninic acids as intermediates in quinolinemethanol syntheses Robert B. Fugitt and Royston M. Roberts pp 875 - 879; DOI: 10.1021/jm00266a002 |
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Quinazolines and 1,4-benzodiazepines. 58. Azido group, a novel pharmacophoric substituent. 7-Azido-5-phenyl-1,4-benzodiazepines Robert Y. Ning, Leo H. Sternbach, William Pool, and Lowell O. Randall pp 879 - 882; DOI: 10.1021/jm00266a003 |
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N-Substituted 2-amino-1-(2-thienyl)ethanols as .beta.-adrenergic blocking agents C. Corral, V. Darias, M. P. Fernandez-Tome, R. Madronero, and J. Del Rio pp 882 - 885; DOI: 10.1021/jm00266a004 |
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Benzhydryl and fluorenyl lactamimides with hypoglycemic, diuretic, blood platelet aggregation inhibitory, and antiinflammatory activities J. Martin Grisar, George P. Claxton, Norbert L. Wiech, Ronald W. Lucas, Robert D. MacKenzie, and Sidney Goldstein pp 885 - 893; DOI: 10.1021/jm00266a005 |
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Synthesis of .alpha.,.beta.-poly [(2-hydroxyethyl)-DL-aspartamide], a newplasma expander Paolo Neri, Guido Antoni, Franco Benvenuti, Francesco Cocola, and Guido Gazzei pp 893 - 897; DOI: 10.1021/jm00266a006 |
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Long-acting delivery systems for narcotic antagonists. 1 James H. R. Woodland, Seymour Yolles, David A. Blake, Martin Helrich, and Francis J. Meyer pp 897 - 901; DOI: 10.1021/jm00266a007 |
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Antihypertensive agents. Synthesis and biological properties of 2-amino-4-aryl-2-imidazolines W. L. Matier, D. A. Owens, W. T. Comer, D. Deitchman, H. C. Ferguson, R. J. Seidehamel, and J. R. Young pp 901 - 908; DOI: 10.1021/jm00266a008 |
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Urinary metabolites of DL-methadone in maintenance subjects Hugh R. Sullivan and Susan L. Due pp 909 - 913; DOI: 10.1021/jm00266a009 |
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Tumor inhibitors. 89. Structural requirements for tumor-inhibitory activity among benzylisoquinoline alkaloids and related synthetic compounds S. Morris Kupchan and Henry W. Altland pp 913 - 917; DOI: 10.1021/jm00266a010 |
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Structure-activity relation of chloramphenicols Corwin Hansch, Kenneth Nakamoto, Michael Gorin, Peter Denisevich, Edward R. Garrett, S. M. Heman-Ackah, and C. H. Won pp 917 - 922; DOI: 10.1021/jm00266a011 |
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Structure-activity relations. 6. Structure-activity relations of monoamine oxidase inhibitors Toshio Fujita pp 923 - 930; DOI: 10.1021/jm00266a012 |
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New nonsteroidal antiinflammatory agent. 2-Substituted 5- or 6-benzothiazoleacetic acids and their derivatives Jin Wada, Tadayuki Suzuki, Morio Iwasaki, Hiroki Miyamatsu, Shinji Ueno, and Mitsuhiro Shimizu pp 930 - 934; DOI: 10.1021/jm00266a013 |
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Synthesis and antiviral activity of 1,2,4-triazole-3-thiocarboxamide and 1,2,4-triazole-3-carboxamidine ribonucleosides Joseph T. Witkowski, Roland K. Robins, Gyaneshwar P. Khare, and Robert W. Sidwell pp 935 - 937; DOI: 10.1021/jm00266a014 |
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Structure-activity relations in reactivators of organophosphorus-inhibited acetylcholinesterase. 6. 2-Hydroxyiminomethylimidazolium iodides Mario Grifantini, Sante Martelli, and Maria L. Stein pp 937 - 939; DOI: 10.1021/jm00266a015 |
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Structural relations among cytotoxic and antitumor benzophenanthridine alkaloid derivatives Frank R. Stermitz, Kenneth A. Larson, and Don K. Kim pp 939 - 940; DOI: 10.1021/jm00266a016 |
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Preparation and antimalarial activity of some derivatives of 6-bromo-.alpha.-(di-n-heptylaminomethyl)-9-phenanthrenemethanol Robert E. Harmon, T. S. Lin, and S. K. Gupta pp 940 - 942; DOI: 10.1021/jm00266a017 |
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Mechanism of narcosis. Entropy of hydration of gaseous general anesthetics Paul Haberfield and Juris Kivuls pp 942 - 945; DOI: 10.1021/jm00266a018 |
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Potential organ- or tumor-imaging agents. 13. 19-Radioiodinated sterols R. E. Counsell, P. G. Kulkarni, P. Afiatpour, and V. V. Ranade pp 945 - 947; DOI: 10.1021/jm00266a019 |
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Substituted tetralins. 5. Analgesic properties of some diastereoisomeric N,N-dimethyl-4-phenyl-1,2,3,4-tetrahydro-2-naphthylamines E. M. Kandeel and A. R. Martin pp 947 - 948; DOI: 10.1021/jm00266a020 |
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2,4-Dimethyl derivatives of 5-methoxy-3-indolylethylamines. New 5-oxygenated tryptamines George R. Allen, Vern G. De Vries, E. N. Greenblatt, Ruddy Littell, Francis J. McEvoy, and Daniel B. Moran pp 949 - 951; DOI: 10.1021/jm00266a021 |
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Glutaryl-S-(p-bromobenzyl)-L-cysteinylglycine. Metabolically stable inhibitor of glyoxalase I Robert Vince, Mark Wolf, and Connie Sanford pp 951 - 953; DOI: 10.1021/jm00266a022 |
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Synthesis of 3-(aminoalkyl)-1-[(5-nitrofurfurylidene)amino]hydantoins Claude F. Spencer, Julian G. Michels, George C. Wright, and Chia-Nien Yu pp 953 - 956; DOI: 10.1021/jm00266a023 |
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Synthesis of 5'-phosphates of the naturally occurring 6-ureidopurine ribonucleosides and their analogs Chung Il Hong and Girish B. Chheda pp 956 - 959; DOI: 10.1021/jm00266a024 |
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Guanylhydrazones with potential antileukemic activity. 1. Aza analogs of 4,4'-diacetyldiphenylurea bis(guanylhydrazone) W. Korytnyk, A. C. Ghosh, N. Angelino, and C. Dave pp 959 - 961; DOI: 10.1021/jm00266a025 |
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Book Reviews pp 961 - 962; DOI: 10.1021/jm00266a600 |
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Conformationally restricted analogs of histamine H1 receptor antagonists. trans- and cis-1,5-Diphenyl-3-dimethylaminopyrrolidine Patrick E. Hanna and Ahmed E. Ahmed pp 963 - 968; DOI: 10.1021/jm00267a001 |
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Angiotensin II. Synthesis and biological activity of 6-(1-methylhistidine) and 6-(3-methylhistidine) analogs Philip Needleman, Garland R. Marshall, and Jean Rivier pp 968 - 970; DOI: 10.1021/jm00267a002 |
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Diamidino-.alpha.,.omega.-diphenoxyalkanes. Structure-activity relations for the inhibition of thrombin, pancreatic kallikrein, and trypsin J. D. Geratz, Alan C. Whitmore, Michael C. F. Cheng, and Claude Piantadosi pp 970 - 975; DOI: 10.1021/jm00267a003 |
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Solid phase synthesis of [1-deamino,4-valine]-8-D-arginine-vasopressin (DVDAVP), a highly potent and specific antidiuretic agent possessing protracted effects Maurice Manning, Lajos Balaspiri, Margot Acosta, and Wilbur H. Sawyer pp 975 - 978; DOI: 10.1021/jm00267a004 |
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Synthetic penicillins. Heterocyclic analogs of ampicillin. Structure-activity relations Minoru Hatanaka and Toshiyasu Ishimaru pp 978 - 984; DOI: 10.1021/jm00267a005 |
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Heterocyclic thiosemicarbazones and related derivatives. Synthesis and screening data A. Giner-Sorolla, M. McCravey, J. Longley-Cook, and J. H. Burchenal pp 984 - 988; DOI: 10.1021/jm00267a006 |
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Coenzyme Q. 165. Antimetabolites of coenzyme Q. 18. Synthesis and inhibitory activity of new ethylenedioxyquinones as analogs of coenzyme Q Christine M. Bowman, Ronald J. Wikholm, Jan Boler, Conny B. Bogentoft, and Karl Folkers pp 988 - 991; DOI: 10.1021/jm00267a007 |
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Acid-labile derivatives of chloramphenicol as potential latentiation forms Andree D. Gillet and Mahmoud M. Abdel-Monem pp 992 - 995; DOI: 10.1021/jm00267a008 |
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Metabolites of methyl 5(6)-butyl-2-benzimidazolecarbamate (parbendazole). Structure and synthesis George L. Dunn, Gregory Gallagher, Larry D. Davis, John R. E. Hoover, and R. John Stedman pp 996 - 1002; DOI: 10.1021/jm00267a009 |
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5,8-Disubstituted 1-aminotetralins. Class of compounds with a novel profile of central nervous system activity Reinhard Sarges, James R. Tretter, Stanley S. Tenen, and Albert Weissman pp 1003 - 1011; DOI: 10.1021/jm00267a010 |
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Benzodiazepines with psychotropic activity. 7. Synthesis and biological action of 4-amino-1,5-benzodiazepines Adolf Bauer, Peter Danneberg, Karl Heinz Weber, and Klaus Minck pp 1011 - 1014; DOI: 10.1021/jm00267a011 |
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Lysergic acid and quinidine analogs. 2-(o-Acylaminophenethyl)piperidines Stanley J. Dykstra, Joseph L. Minielli, John E. Lawson, Hugh C. Ferguson, and Kendrick W. Dungan pp 1015 - 1020; DOI: 10.1021/jm00267a012 |
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.beta.-Adrenergic blocking agents. 14. Microbiological reduction of isopropylaminomethyl 2-naphthyl ketone to (R)-(-)-2-isopropylamino-1-(2-naphthyl)ethanol and related reductions Ralph Howe, Ronald H. Moore, and Balbir S. Rao pp 1020 - 1023; DOI: 10.1021/jm00267a013 |
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Conformational requirements for direct adrenergic stimulation Allan P. Gray, Ernest Reit, John A. Ackerly, and Milos Hava pp 1023 - 1027; DOI: 10.1021/jm00267a014 |
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Antiparasitic 5-nitrothiazoles and 5-nitro-4-thiazolines. 2 Peter J. Islip, Michael D. Closier, and John E. Weale pp 1027 - 1030; DOI: 10.1021/jm00267a015 |
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Antiparasitic 5-nitrothiazoles and 5-nitro-4-thiazolines. 3 Peter J. Islip, Michael D. Closier, and Martin C. Neville pp 1030 - 1034; DOI: 10.1021/jm00267a016 |
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Molecular orbital calculations on suspected intermediates in oxidative amine metabolism Sidney D. Nelson, Peter A. Kollman, William F. Trager, and Stephen Rothenberg pp 1034 - 1037; DOI: 10.1021/jm00267a017 |
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Antimalarials. 5. 2-Aryl-6-trifluoromethy-1-4-pyridinemethanols M. P. LaMontagne, A. Markovac, and M. S. Ao pp 1040 - 1041; DOI: 10.1021/jm00267a018 |
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Thiosulfuric acid analog of quinine as a potential antimalarial agent Daniel L. Klayman, T. Scott Griffin, J. David Bower, and Samuel W. Page pp 1042 - 1043; DOI: 10.1021/jm00267a019 |
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Synthesis and microbiological properties of 3-amino-1-hydroxy-2-indolinone and related compounds Alvie L. Davis, David R. Smith, and Tommy J. McCord pp 1043 - 1045; DOI: 10.1021/jm00267a020 |
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Synthesis and central nervous system depressant activity of some 2-aryl-6-chloro-4-phenylquinazolines Hans Kohl, Noel J. De Souza, and Premanand D. Desai pp 1045 - 1047; DOI: 10.1021/jm00267a021 |
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Synthesis and antiviral activity of homologs of noformycin Guy D. Diana, Urano J. Salvador, Ethel S. Zalay, and Francis Pancic pp 1050 - 1053; DOI: 10.1021/jm00267a022 |
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Synthesis of bradykinin via oximinopyrazoline active esters (OPmp) Roberto Tomatis, Roberto Ferroni, Mario Guarneri, and Carlo A. Benassi pp 1053 - 1054; DOI: 10.1021/jm00267a023 |
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Improved solid-phase synthesis of the luteinizing-hormone releasing-hormone/follicle-stimulating hormone releasing-hormone (LH-RH/FSH-RH) William H. Arnold, Wilfrid White, and George Flouret pp 1054 - 1055; DOI: 10.1021/jm00267a024 |
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Heterocyclic N-glycosyl derivatives. 15. Synthesis of unsaturated 6-methylthiopurine nucleosides Gregorio Alonso, Mercedes Fuertes, Guillermo Garcia-Munoz, Ramon Madronero, and Manfred Stud pp 1056 - 1057; DOI: 10.1021/jm00267a025 |
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.beta.-Chloroethylamines related to mescaline Paul D. Cooper pp 1057 - 1059; DOI: 10.1021/jm00267a026 |
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N-Substituted derivatives of erythromycylamine R. Ryden, Graham H. Timms, Diana M. Prime, and Eric Wildsmith pp 1059 - 1060; DOI: 10.1021/jm00267a027 |
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Antimicrobial action of isomeric fatty acids on group A Streptococcus Jon J. Kabara, Anthony J. Conley, Dennis M. Swieczkowski, I. A. Ismail, M. Lie Ken Jie, and Frank D. Gunstone pp 1060 - 1063; DOI: 10.1021/jm00267a028 |
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Quaternary salts of substituted 2-aminoethyl N-benzoylaminobenzoate. New class of smooth muscle relaxant agents Mario Ghelardoni, Vittorio Pestellini, Nicola Pisanti, and Giovanna Volterra pp 1063 - 1065; DOI: 10.1021/jm00267a029 |
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Effects of Small Changes in Chemical Structure on Stereospecificity R.B. Barlow pp 1037 - 1038; DOI: 10.1021/jm00267a600 |
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Potential Organ- or Tumor-Imaging Agents. 14. Myocardial Scanning Agents R.E. Counsell, Terry Yu, V.V. Ranade, and A. Buswink pp 1038 - 1040; DOI: 10.1021/jm00267a601 |
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Structure and Anticoccidial Activity of a New Series of 4-Hydroxyquinoline-3-carboxylates Bert K.F. Hermans, Marcel A.C. Janssen, Hugo L.E. Verhoeven, Alfons G. Knaeps, Theo T.J.M. Van Offenwert, Jozef H. Mostmans, Johan J.M. Willems, Bert Maes, and Oscar Vanparijis pp 1047 - 1050; DOI: 10.1021/jm00267a602 |
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Book Reviews pp 1066 - 1070; DOI: 10.1021/jm00267a603 |
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Synthesis of some rifamycin derivatives as inhibitors of an RNA-instructed DNA polymerase function Allan N. Ischler, Urs R. Joss, Frances M. Thompson, and Melvin Calvin pp 1071 - 1075; DOI: 10.1021/jm00268a001 |
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Synthesis and biological activity of certain carbamoyl and alkoxycarbonyl derivatives of adenosine 3',5'-cyclic phosphate Kay H. Boswell, Jon P. Miller, Dennis A. Shuman, Robert W. Sidwell, Lionel N. Simon, and Roland K. Robins pp 1075 - 1079; DOI: 10.1021/jm00268a002 |
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Hydrolysis of hydroxybenzotrifluorides and fluorinated uracil derivatives. General mechanism for carbon-fluorine bond labilization Ted T. Sakai and Daniel V. Santi pp 1079 - 1084; DOI: 10.1021/jm00268a003 |
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Oxidation of furans. 2. Synthesis and biological properties of 6-hydroxy-2H-pyran-3(6H)-ones and derivatives Real Laliberte, Geroges Medawar, and Yvon Lefebvre pp 1084 - 1089; DOI: 10.1021/jm00268a004 |
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Relation between physical properties and antimalarial activities of 1,4-naphthoquinones Yvonne C. Martin, Thomas M. Bustard, and Kathleen R. Lynn pp 1089 - 1093; DOI: 10.1021/jm00268a005 |
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Further side-chain modification of antimalarial phenanthrene amino alcohols Ping-Lu Chien and C. C. Cheng pp 1093 - 1096; DOI: 10.1021/jm00268a006 |
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Chemistry and biology of vitamin B6. 33. General method for modifying the 2-methyl group of pyridoxol. Synthesis and biological activity of 2-vinyl- and 2-ethynylpyridoxols and related compounds W. Korytnyk, S. C. Srivastava, N. Angelino, P. G. G. Potti, and B. Paul pp 1096 - 1101; DOI: 10.1021/jm00268a007 |
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Comparative inhibition of thrombin, plasmin, trypsin, and complement by benzamidines using substituent constants and regression analysis Eugene A. Coats pp 1102 - 1106; DOI: 10.1021/jm00268a008 |
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In vivo metabolite condensations. Formation of N1-ethyl-2-methyl-N3-(2,6-dimethylphenyl)-4-imidazolidinone from the reaction of a metabolite of alcohol with a metabolite of lidocaine Sidney D. Nelson, George D. Breck, and William F. Trager pp 1106 - 1112; DOI: 10.1021/jm00268a009 |
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b-Adrenergic blocking agents. Nitrogen heteroaryl-substituted 2-propanolamines and ethanolamines Robert F. Meyer, Charlotte D. Stratton, Stephen G. Hastings, and Ruth M. Corey pp 1113 - 1116; DOI: 10.1021/jm00268a010 |
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Pancuronium bromide and other steroidal neuromuscular blocking agents containing acetylcholine fragments W. R. Buckett, C. L. Hewett, and D. S. Savage pp 1116 - 1124; DOI: 10.1021/jm00268a011 |
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Synthesis and central nervous system depressant activity of some 5-(2-substituted alkyl)-2-oxazolidinones Marvel L. Fielden, William J. Welstead, Norman D. Dawson, Ying-Ho Chen, Richard P. Mays, John P. DaVanzo, and Carl D. Lunsford pp 1124 - 1128; DOI: 10.1021/jm00268a012 |
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5-(2-Aminoethyl)-2-oxazolidinones with central nervous system depressant and antiinflammatory activity William J. Welstead, Grover C. Helsley, C. Roy Taylor, Lennox B. Turnbull, John P. Da Vanzo, William H. Funderburk, and R. S. Alphin pp 1129 - 1132; DOI: 10.1021/jm00268a013 |
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New benzothiazines. 4. 1H-2,3-Benzothiazin-4(3H)-one 2,2-dioxide and 2H-1,2-benzothiazin-3(4H)-one 1,1-dioxide nitrogen derivatives with central nervous system activity Enrico Sianesi, Riccardo Redaelli, Maria J. Magistretti, and Elena Massarani pp 1133 - 1137; DOI: 10.1021/jm00268a014 |
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Synthesis of the thyrotropin-releasing hormone enantiomer and some diastereoisomers and in vitro studies of their biological activity G. Flouret, R. Morgan, R. Gendrich, J. Wilber, and M. Seibel pp 1137 - 1140; DOI: 10.1021/jm00268a015 |
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Effect of simple amino acid replacements on the biological activity of luteinizing hormone-releasing hormone David H. Coy, Esther J. Coy, and Andrew V. Schally pp 1140 - 1143; DOI: 10.1021/jm00268a016 |
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Structure-activity relations in the C-terminal part of luteinizing hormone-releasing hormone Masahiko Fujino, Susumu Shinagawa, Mikihiko Obayashi, Shigeru Kobayashi, Tsunehiko Fukukda, Iwao Yamazaki, Ryo Nakayama, Wilfrid F. White, and Riemond H. Rippel pp 1144 - 1147; DOI: 10.1021/jm00268a017 |
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Synthesis and structure-activity relationship of some thiol adducts of ethacrynic acid Daniel A. Koechel and Edward J. Cafruny pp 1147 - 1152; DOI: 10.1021/jm00268a018 |
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Biologically oriented organic sulfur chemistry. 12. Principles of structure-activity relations for penicillamine analogs and derivatives Lamar Field, Wayne S. Hanley, Phillip L. Kelly, William J. Sanders, Jerry E. White, Israeli A. Jaffe, and Parvin Merryman pp 1152 - 1157; DOI: 10.1021/jm00268a019 |
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Metabolism of 5-(p-hydroxyanilino)-1,2,3,4-thiatriazole in rats George J. Ikeda pp 1157 - 1161; DOI: 10.1021/jm00268a020 |
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Synthesis of antimicrobial nitroimidazolyl 2-sulfides, -sulfoxides, and -sulfones Robert C. Tweit, E. M. Kreider, and R. D. Muir pp 1161 - 1169; DOI: 10.1021/jm00268a021 |
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Aminobenzoic acid diuretics. 5. 3-Amino-4-arylmethyl-5-sulfamylbenzoic acid derivatives and related compounds Ole B. Tvaermose Nielsen, Christian Kaergaard Nielsen, and Peter W. Feit pp 1170 - 1177; DOI: 10.1021/jm00268a022 |
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Analgetics based on the pyrrolidine ring. 8 Ralph E. Bowman, Harry O. J. Collier, Peter J. Hattersley, Ian M. Lockhart, David J. Peters, Cyril Schneider, Nigel E. Webb, and Michael Wright pp 1177 - 1180; DOI: 10.1021/jm00268a023 |
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Analgetics based on the pyrrolidine ring. 9 Ralph E. Bowman, Harry O. J. Collier, Ian M. Lockhart, Cyril Schneider, Nigel E. Webb, and Michael Wright pp 1181 - 1183; DOI: 10.1021/jm00268a024 |
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Solid-phase synthesis of [3-proline,8-isoleucine]-, [1-sarcosine,3-proline, 8-isoleucine]-, and [4-phenylalanine,8-isoleucine]angiotensin II as the antagonists of the parent hormone M. C. Khosla, M. M. Hall, R. R. Smeby, and F. M. Bumpus pp 1184 - 1185; DOI: 10.1021/jm00268a025 |
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Synthesis of diethyl N-dodecylphosphoramidate analogs as potential inhibitors of dental plaque Victor D. Warner, Dale B. Mirth, Adrienne S. Dey, Samuel S. Turesky, and Barbara Soloway pp 1185 - 1186; DOI: 10.1021/jm00268a026 |
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Fibrin-stabilizing factor inhibitors. 10. Thiol esters as potent enzyme inhibitors Christine Ljunggren, Kurt Juergen Hoffmann, Pal Stenberg, and J. Lars G. Nilsson pp 1186 - 1188; DOI: 10.1021/jm00268a027 |
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Three new adenosine triphosphate analogs. Synthesis and effects on isolated gut Geoffrey R. Gough, M. Helen Maguire, and David G. Satchell pp 1188 - 1190; DOI: 10.1021/jm00268a028 |
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Methotrexate analogs. 2. Facile method of preparation of lipophilic derivatives of methotrexate and 3',5'-dichloromethotrexate by direct esterification A. Rosowsky pp 1190 - 1193; DOI: 10.1021/jm00268a029 |
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Book Reviews pp 1193 - 1194; DOI: 10.1021/jm00268a600 |
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Electronic structures of cephalosporins and penicillins. 2. Disulfide and .beta.-lactam chromophores. Structure-activity relations Donald B. Boyd pp 1195 - 1199; DOI: 10.1021/jm00269a001 |
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Cannabinoids. Structure-activity studies related to 1,2-dimethylheptyl derivatives Bernard Loev, Paul E. Bender, Frederick Dowalo, Edward Macko, and Philip J. Fowler pp 1200 - 1206; DOI: 10.1021/jm00269a002 |
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Aromatic substituent constants for structure-activity correlations Corwin Hansch, Albert Leo, Stefan H. Unger, Ki Hwai Kim, Donald Nikaitani, and Eric J. Lien pp 1207 - 1216; DOI: 10.1021/jm00269a003 |
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Strategy in drug design. Cluster anlysis as an aid in the selection of substituents Corwin Hansch, Stefan H. Unger, and Alan B. Forsythe pp 1217 - 1222; DOI: 10.1021/jm00269a004 |
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Synthesis of 5-substituted quinazolines as potential antimalarial agents Wallace T. Ashton and John B. Hynes pp 1233 - 1237; DOI: 10.1021/jm00269a005 |
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Synthesis and antiinflammatory activity of 1-alkyl-4-aryl-2(1H)-quinazolines and quinazolinethiones R. V. Coombs, R. P. Danna, M. Denzer, G. E. Hardtmann, B. Huegi, G. Koletar, J. Koletar, H. Ott, E. Jukniewicz, and et al. pp 1237 - 1245; DOI: 10.1021/jm00269a006 |
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.beta.-Adrenoceptor blocking agents. 1. Cardioselective 1-aryloxy-3-(aryloxyalkylamino)propan-2-ols J. Augstein, D. A. Cox, A. L. Ham, P. R. Leeming, and M. Sanrey pp 1245 - 1251; DOI: 10.1021/jm00269a007 |
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Partly reduced biphenyls as central nervous system agents. 3. cis- and trans-4-Aryl-4-methoxycyclohexylamines Daniel Lednicer, D. Edward Emmert, Robert Lahti, and Allan D. Rudzik pp 1251 - 1256; DOI: 10.1021/jm00269a008 |
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Central nervous system depressants. 11. Benzodiazepines with ureas in the 2 position Robert B. Moffett and Allan D. Rudzik pp 1256 - 1260; DOI: 10.1021/jm00269a009 |
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Potential bioreductive alkylating agents. 2. Antitumor effect and biochemical studies of naphthoquinone derivatives Ai Jeng Lin, Ronald S. Pardini, Lucille A. Cosby, Brian J. Lillis, Charles W. Shansky, and Alan C. Sartorelli pp 1268 - 1271; DOI: 10.1021/jm00269a010 |
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Potential histamine H2-receptor antagonists. 1. Aminoethylimidazo[1,2-a]pyridines and -imidazo[1,5-a]pyridines Graham J. Durant, John M. Loynes, and Stanley H. B. Wright pp 1272 - 1276; DOI: 10.1021/jm00269a011 |
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New asparagine analogs Pauline K. Chang, Louis J. Sciarini, and Robert E. Handschumacher pp 1277 - 1280; DOI: 10.1021/jm00269a012 |
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Synthesis and antitumor and antibacterial activity of benzoquinones related to the mitomycins Thomas R. Witty and William A. Remers pp 1280 - 1284; DOI: 10.1021/jm00269a013 |
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Synthetic sweeteners. 3. Aspartyl dipeptide esters from L- and D-alkylglycines Robert H. Mazur, Judith A. Reuter, Kenneth A. Swiatek, and James M. Schlatter pp 1284 - 1287; DOI: 10.1021/jm00269a014 |
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Chemotherapeutic nitroheterocycles. Antischistosomal properties of nitrofurylvinyl and nitrothienylvinyl heterocycles D. W. Henry, V. H. Brown, M. Cory, J. G. Johansson, and E. Bueding pp 1287 - 1291; DOI: 10.1021/jm00269a015 |
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Compound 48/80. Structure-activity relations and poly-THIQ [tetrahydroisoquinoline], a new, more potent analog George W. Read, Edgar F. Kiefer, and James F. Weber pp 1292 - 1295; DOI: 10.1021/jm00269a016 |
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Antiviral. 1. 2-(.alpha.-Hydroxybenzyl)imidazo[4,5-c]pyridine Heinz Berner, Hellmuth Reinshagen, and Meinrad A. Koch pp 1296 - 1298; DOI: 10.1021/jm00269a017 |
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Pyrrole antibacterial agents. 1. Compounds related to pyoluteorin Denis M. Bailey, Robert E. Johnson, and U. Joseph Salvador pp 1298 - 1300; DOI: 10.1021/jm00269a018 |
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Pyrrole antibacterial agents. 2. 4,5-Dihalopyrrole-2-carboxylic acid derivatives Denis M. Bailey and Robert E. Johnson pp 1300 - 1302; DOI: 10.1021/jm00269a019 |
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14.alpha.,17.alpha.-Alkylidenedioxy steroids. 2. 19-Nor-9.alpha.,10.beta.- and 19-nor-9.beta.,10.alpha.-progesterone analogs Arthur F. Marx, Herman J. Kooreman, Kapil D. Jaitly, and Dirk Van der Sijde pp 1302 - 1305; DOI: 10.1021/jm00269a020 |
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Bis(dimethylamino)-s-triazinyl antiinflammatory agents Rachael Vanderhoek, George Allen, and Joseph A. Settepani pp 1305 - 1306; DOI: 10.1021/jm00269a021 |
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Ethyl adenosine-5'-carboxylate. Potent vasoactive agent in the dog Herman H. Stein pp 1306 - 1308; DOI: 10.1021/jm00269a022 |
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Nitrofuryl heterocyclics. 3 Peter J. Islip and Madelaine R. Johnson pp 1308 - 1310; DOI: 10.1021/jm00269a023 |
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Antimetabolites of coenzyme Q. 20. Synthesis of new alkyl-5,8-quinoxalinequinones as potential inhibitors of coenzyme Q and as antimalarial drugs Thomas H. Porter, Alexander Von Klaudy, and Karll Folkers pp 1310 - 1311; DOI: 10.1021/jm00269a024 |
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Deaza analogs of some 4-, 6-, and 8-aminoquinolines Daniel J. McCaustland, Ping-Lu Chien, C. C. Cheng, Jaroslav Novotny, Walter L. Schreiner, and Fred W. Starks pp 1311 - 1314; DOI: 10.1021/jm00269a025 |
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Coenzyme Q. 166. Antimetabolites of coenzyme Q. 21. Synthesis of alkyl-4,7-dioxobenzothiazoles with prophylactic antimalarial activity Martin D. Friedman, Philip L. Stotter, Thomas H. Porter, and Karl Folkers pp 1314 - 1316; DOI: 10.1021/jm00269a026 |
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Acute oral toxicity of 2-alkyl- and 2,6-dialkylanilines. Correlation with lipophilicity John A. Durden pp 1316 - 1316; DOI: 10.1021/jm00269a027 |
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Compounds Affecting the Central Nervous System. 4. 3.beta.-Phenyltropane-2-carboxylic Esters and Analogs Robert L. Clarke, Sol J. Daum, Anthony J. Gambino, Mario D. Aceto, Jack Pearl, Morton Levitt, Wayne R. Cuminskey, and Eugenio F. Bogado pp 1260 - 1267; DOI: 10.1021/jm00269a600 |
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Aporphines. 8. Total Synthesis and Pharmacological Evaluation of (±)-Apomorphine, (±)-Apocodeine, (±)-N-n-Propylnorapomorphine, and (±)-N-n--Propylnorapocodeine John L. Neumeyer, Bernard R. Neustadt, Kyung H. Oh, Klaus W. Weinhardt, Charles B. Boyce, Franklin J. Rosenberg, and David G. Teiger pp 1223 - 1228; DOI: 10.1021/jm00269a601 |
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Aporphines. 9. Synthesis and Pharmacological Evaluation of (±) 9, 10-Dihydroxyaporphine [(±)-Isoapomorphine], (±)-,(-)-, and (±)-1,2-Dihydroxyaporphine, and (+)-1, 2, 9, 10 - Tetrahydroxyaporphine. John L. Neumeyer, Monica McCarthy, Sam P. Battista, Franklin J. Rosenberg, and David G. Teiger pp 1228 - 1233; DOI: 10.1021/jm00269a602 |
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Book Reviews pp 1317 - 1318; DOI: 10.1021/jm00269a603 |
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Synthesis and enzymic studies of 5-aminoimidazole and N-1- and N6-substituted adenine ribonucleoside cyclic 3',5'-phosphates prepared from adenosine cyclic 3',5'-phosphate Rich B. Meyer, Dennis A. Shuman, Roland K. Robins, Jon P. Miller, and Lionel N. Simon pp 1319 - 1323; DOI: 10.1021/jm00270a001 |
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Synthesis and hormonal activities of 8-L-homonorleucine-vasopressin Mary L. Fink and Miklos Bodanszyky pp 1324 - 1326; DOI: 10.1021/jm00270a002 |
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Lipolytic activity of Met-Arg-His-Phe-Arg-Trp-Gly, a synthetic analog of the ACTH (4-10) core sequence Michael W. Draper, R. B. Merrifield, and Martin A. Rizack pp 1326 - 1330; DOI: 10.1021/jm00270a003 |
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2-Aminoindans of pharmacological interest Everett Solomons and Joseph Sam pp 1330 - 1333; DOI: 10.1021/jm00270a004 |
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Antiallergic activity of 2-nitroindan-1,3-diones Derek R. Buckle, Neil J. Morgan, Janet W. Ross, Harry Smith, and Barbara A. Spicer pp 1334 - 1339; DOI: 10.1021/jm00270a005 |
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Potential antidiabetic agents. Pyrazolo[3,4-b]pyridines H. Hoehn, I. Polacek, and E. Schulze pp 1340 - 1346; DOI: 10.1021/jm00270a006 |
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Pyrazolodiazepines. 1,3-(and 2,3-) Dialkyl-4,6-dihydro-8-arylpyrazolo[4,3-e][1,4]diazepin-5-ones as antianxiety agents Horace A. DeWald, Ivan C. Nordin, Yvon J. L'Italien, and Robert F. Parcell pp 1346 - 1354; DOI: 10.1021/jm00270a007 |
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1-Poly(fluoroalkyl)benzodiazepines Martin Steinman, John G. Topliss, Robert Alekel, Yee-Shing Wong, and Eunice E. York pp 1354 - 1360; DOI: 10.1021/jm00270a008 |
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Naphthothiophenes. 3. Preparation of 4-naphtho[1,2-b]thiophenemethanols and 5-naphtho[1,2-b]thiophenemethanols and attempts to prepare 5-naphtho[2,1-b]thiophenemethanols as antimalarials Bijan P. Das, Robert T. Cunningham, and David W. Boykin pp 1361 - 1365; DOI: 10.1021/jm00270a009 |
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Effect of ring and side chain substituents on the binding of naphthothiopheneethanolamines to deoxyribonucleic acid. Spectrophotometric studies James W. Panter, David W. Boykin, and W. David Wilson pp 1366 - 1369; DOI: 10.1021/jm00270a010 |
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Influence of 6-azido and 6-thiocyanato substitution on progestational and corticoid activities and a structure-activity correlation in the .DELTA.6-6-substituted progestational series George Teutsch, Lois Weber, Geoffrey Page, Elliot L. Shapiro, Hershel L. Herzog, Rudolph Neri, and Elliot J. Collins pp 1370 - 1376; DOI: 10.1021/jm00270a011 |
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N-Alkylnorketobemidones with strong agonist and weak antagonist properties Tokuro Ohishi and Everette L. May pp 1376 - 1378; DOI: 10.1021/jm00270a012 |
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Anticonvulsants. 4. Metharbital and phenobarbital derivatives Julius A. Vida, Mary L. Hooker, Carlos M. Samour, and John F. Reinhard pp 1378 - 1381; DOI: 10.1021/jm00270a013 |
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Platelet aggregation inhibitors. 6. 2-Thioadenosine derivatives Kiyomi Kikugawa, Hideo Suehiro, and Motonobu Ichino pp 1381 - 1388; DOI: 10.1021/jm00270a014 |
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Platelet aggregation inhibitors. 7. S-Substituted 2-thioadenosine 5'-monophosphates Kiyomi Kikugawa, Hideo Suehiro, and Mostonobu Ichino pp 1389 - 1391; DOI: 10.1021/jm00270a015 |
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Synthesis of 1,4-bis(6-methoxy-8-quinolylaminoalkyl)piperazines as potential prophylactic antimalarial agents Kalidas Paul and C. DeWitt Blanton pp 1391 - 1394; DOI: 10.1021/jm00270a016 |
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Preliminary pharmacology of benzocycloheptane derivatives related to amphetamine R. M. Parkhurst, Priscilla A. Sturm, Howard Johnson, and W. A. Skinner pp 1394 - 1396; DOI: 10.1021/jm00270a017 |
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Puromycin analogs. Synthesis and biological activity of 5'-deoxypuromycin and its aminonucleoside, 6-dimethylamino-9-(3'-amino-3',5'-dideoxy-.beta.-D-ribofuranosyl)purine Ronald G. Almquist and Robert Vince pp 1396 - 1399; DOI: 10.1021/jm00270a018 |
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Effect of trifluoromethoxy, chlorodifluoromethoxy, and trifluoromethyl on the antimalarial activity of 5-benzyl- and 5-phenyl-2,4-diaminopyrimidines Eugene L. Stogryn pp 1399 - 1401; DOI: 10.1021/jm00270a019 |
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Thiourea derivatives of 2-aminooxazoles showing antibacterial and antifungal activity George Crank, Martin Neville, and Ray Ryden pp 1402 - 1405; DOI: 10.1021/jm00270a020 |
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5-Hydroxymethyltubercidin. Synthesis, biological activity, and role in pyrrolopyrimidine biosynthesis Takayoshi Uematsu and Robert J. Suhadolnik pp 1405 - 1407; DOI: 10.1021/jm00270a021 |
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Amino acid analogs. 2. 3-Fluoroamino acids. 1. Chain length three to seven carbon atoms Herman Gershon, Maynard W. McNeil, and E. D. Bergmann pp 1407 - 1409; DOI: 10.1021/jm00270a022 |
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Probiotics. Antistaphylococcal and antifibrinolytic activities of .omega.-guanidino acids and .omega.-guanidinoacyl-L-histidines Akira Fujii and Elton S. Cook pp 1409 - 1411; DOI: 10.1021/jm00270a023 |
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Synthetic trypanocides. 3. Structure-activity relations Nora Poliakoff, Sem M. Albonico, Manuel Alvarez, Jorge Gallo Pecca, and Marcelo J. Vernengo pp 1411 - 1413; DOI: 10.1021/jm00270a024 |
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Synthesis of cephapirin and related cephalosporins from 7-(.alpha.-bromoacetamido)cephalosporanic acid Leonard B. Crast, Robert G. Graham, and Lee C. Cheney pp 1413 - 1415; DOI: 10.1021/jm00270a025 |
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Additions and Corrections. Synthesis and Oral Hypoglycemic Activity of N-(p-Deuteriomethylbenzenesulfonyl)-N'-n-butylurea, Deuterium-Substituted Tolbutamide. Raymond D. Kimbrough, Jr. pp 1415 - 1415; DOI: 10.1021/jm00270a600 |
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Additions and Corrections. Studies on the Synthesis of Heterocylic Compounds. 459. Synthesis of Rescinnamine-Like Compouns as Antihypertensive Agents T. Kametani, M. Ihara, T. Suzuki, T. Takahashi, R. Iwaki, H. Takei, N. Miyake, M. Yoshida, Y. Hasegawa, and H. Kitagawa pp 1415 - 1415; DOI: 10.1021/jm00270a601 |
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Additions and Corrections. Cycloprop[16α, 17α]androstanes. Kenneth E. Fahrenholtz, Kenneth P. Meyers, and R. W. Kierstead pp 1415 - 1415; DOI: 10.1021/jm00270a602 |
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Additions and Corrections. Synthesis and Analgetic Activity of the Diastereomeric 8-Hydroxy-6, 7-benzomorphans. Jon J. Fauley, and Jules B. LaPidus pp 1416 - 1416; DOI: 10.1021/jm00270a603 |
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Additions and Correction. Stereo-chemical Studies on Medicinal Agents. 12. The Distinction of Enantiotopic Groups in the Interaction of 1-Methyl-4-phenyl-4-propionoxypiperidine with Analgetic Receptors. Dennis L. Larson, and Philip S. Portoghese pp 1416 - 1416; DOI: 10.1021/jm00270a604 |
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Additions and Corrections. Anticancer Compounds. Furthur Analogs of 1-(4-Dimethylaminobenzylidene)imdene. Carl T. Bahner, Norma H. Bingham, David H. Brotherton, Jane Cline, Dan Darby, Harry D. Harmon, Lydia M. Rives, Bill L. Stump, Stuart L. Watson, Jr., and Thomas E. Harmon pp 1416 - 1416; DOI: 10.1021/jm00270a605 |